A ultrassonografia renal a cada 3 meses, desde o nascimento até os 7 anos de idade, é recomendada para crianças com síndrome predisponente ao tumor de Wilms.[38]Brzezinski JJ, Becktell KD, Bougeard G, et al. Update on surveillance guidelines in emerging Wilms tumor predisposition syndromes. Clin Cancer Res. 2025 Jan 6;31(1):18-24.
https://aacrjournals.org/clincancerres/article/31/1/18/750711/Update-on-Surveillance-Guidelines-in-Emerging
http://www.ncbi.nlm.nih.gov/pubmed/39466169?tool=bestpractice.com
[39]Hol JA, Jewell R, Chowdhury T, et al. Wilms tumour surveillance in at-risk children: literature review and recommendations from the SIOP-Europe Host Genome Working Group and SIOP Renal Tumour Study Group. Eur J Cancer. 2021 Aug;153:51-63.
https://www.ejcancer.com/article/S0959-8049(21)00322-1/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/34134020?tool=bestpractice.com
[100]Kalish JM, Doros L, Helman LJ, et al. Surveillance recommendations for children with overgrowth syndromes and predisposition to Wilms tumors and hepatoblastoma. Clin Cancer Res. 2017 Jul 1;23(13):e115-22.
https://aacrjournals.org/clincancerres/article/23/13/e115/79988/Surveillance-Recommendations-for-Children-with
http://www.ncbi.nlm.nih.gov/pubmed/28674120?tool=bestpractice.com
Deve-se prestar atenção principalmente à identificação de restos nefrogênicos que podem aumentar a probabilidade de evoluir para um tumor de Wilms.[101]Heppe RK, Koyle MA, Beckwith JB. Nephrogenic rests in Wilms tumor patients with the Drash syndrome. J Urol. 1991 Jun;145(6):1225-8.
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[102]Beckwith JB. Nephrogenic rests and the pathogenesis of Wilms tumor: developmental and clinical considerations. Am J Med Genet. 1998 Oct 2;79(4):268-73.
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[103]Beckwith JB. Management of incidentally encountered nephrogenic rests. J Pediatr Hematol Oncol. 2007 Jun;29(6):353-4.
http://www.ncbi.nlm.nih.gov/pubmed/17551393?tool=bestpractice.com
Aconselhamento genético e pré-natal deve ser oferecido aos pais com história familiar de tumor de Wilms.[40]Schienda J, Stopfer J. Cancer genetic counseling-current practice and future challenges. Cold Spring Harb Perspect Med. 2020 Jun 1;10(6):a036541.
https://perspectivesinmedicine.cshlp.org/content/10/6/a036541.long
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[41]Turner JT, Brzezinski J, Dome JS. Wilms tumor predisposition. 2003 Dec 19 (updated 2022 Mar 24). In: Adam MP, Mirzaa GM, Pagon RA, et al, eds. GeneReviews [internet]. Seattle, WA: University of Washington, Seattle; 1993-2023.
https://www.ncbi.nlm.nih.gov/books/NBK1294
http://www.ncbi.nlm.nih.gov/pubmed/20301471?tool=bestpractice.com