Ensaios clínicos envolvendo meninos sugerem que a circuncisão é preventiva.[31]Singh-Grewal D, Macdessi J, Craig J. Circumcision for the prevention of urinary tract infection in boys: a systematic review of randomised trials and observational studies. Arch Dis Child. 2005 Aug;90(8):853-8.
https://adc.bmj.com/content/90/8/853.long
http://www.ncbi.nlm.nih.gov/pubmed/15890696?tool=bestpractice.com
No entanto, não há recomendações claras para homens adultos. Cateteres revestidos em prata ou antibiótico diminuem a bacteriúria associada ao cateter, mas não foi comprovado conclusivamente que previnam a infecção do trato urinário (ITU); portanto, remover ou evitar o uso de cateteres oferece a melhor prevenção.[27]Huang W, Wann S, Lin S, et al. Catheter-associated urinary tract infections in intensive care units can be reduced by prompting physicians to remove unnecessary catheters. Infect Control Hosp Epidemiol. 2004 Nov;25(11):974-8.
http://www.ncbi.nlm.nih.gov/pubmed/15566033?tool=bestpractice.com
[32]Johnson JR, Kuskowski MA, Wilt TJ. Systematic review: antimicrobial urinary catheters to prevent catheter-associated urinary tract infection in hospitalized patients. Ann Intern Med. 2006 Jan 17;144(2):116-26.
http://annals.org/aim/article/719502/systematic-review-antimicrobial-urinary-catheters-prevent-catheter-associated-urinary-tract
http://www.ncbi.nlm.nih.gov/pubmed/16418411?tool=bestpractice.com
[33]Lam TB, Omar M, Fisher E, et al. Types of indwelling urethral catheters for short-term catheterisation in hospitalised adults. Cochrane Database Syst Rev. 2014 Sep 23;(9):CD004013.
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD004013.pub4/full
http://www.ncbi.nlm.nih.gov/pubmed/25248140?tool=bestpractice.com
[34]Drekonja DM, Kuskowski MA, Wilt TJ, et al. Antimicrobial urinary catheters: a systematic review. Exp Rev Med Devices. 2008 Jul;5(4):495-506.
http://www.ncbi.nlm.nih.gov/pubmed/18573048?tool=bestpractice.com
[35]Tenke P, Kovacs B, Bjerklund Johansen TE, et al. European and Asian guidelines on management and prevention of catheter-associated urinary tract infections. Int J Antimicrob Agents. 2008 Feb;31(suppl 1):S68-78.
http://www.ncbi.nlm.nih.gov/pubmed/18006279?tool=bestpractice.com
[36]Stensballe J, Tvede M, Looms D, et al. Infection risk with nitrofurazone-impregnated urinary catheters in trauma patients: a randomized trial. Ann Intern Med. 2007 Sep 4;147(5):285-93.
http://www.ncbi.nlm.nih.gov/pubmed/17785483?tool=bestpractice.com
[37]Pickard R, Lam T, MacLennan G, et al. Antimicrobial catheters for reduction of symptomatic urinary tract infection in adults requiring short-term catheterisation in hospital: a multicentre randomised controlled trial. Lancet. 2012 Dec 1;380(9857):1927-35.
http://www.ncbi.nlm.nih.gov/pubmed/23134837?tool=bestpractice.com
A qualidade e a aplicabilidade das evidências de profilaxia para o uso de várias estratégias de tratamento farmacológico (por exemplo, hipurato de metenamina) e não farmacológico (por exemplo, incentivo da ingestão de suco de oxicoco) na prática clínica para diferentes grupos de pacientes é discutível, pois existem lacunas significativas no conhecimento em relação a subgrupos específicos de homens com ITU. A tentativa desses tratamentos nunca deve impedir a investigação da anormalidade estrutural no trato urinário masculino.[38]Jepson RG, Williams G, Craig JC. Cranberries for preventing urinary tract infections. Cochrane Database Syst Rev. 2012 Oct 17;(10):CD001321.
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD001321.pub5/full
http://www.ncbi.nlm.nih.gov/pubmed/23076891?tool=bestpractice.com
[39]Jepson RG, Craig JC. A systematic review of the evidence for cranberries and blueberries in UTI prevention. Mol Nutr Food Res. 2007 Jun;51(6):738-45.
http://www.ncbi.nlm.nih.gov/pubmed/17492798?tool=bestpractice.com
[40]Lee BS, Bhuta T, Simpson JM, et al. Methenamine hippurate for preventing urinary tract infections. Cochrane Database Syst Rev. 2012 Oct 17;(10):CD003265.
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD003265.pub3/full
http://www.ncbi.nlm.nih.gov/pubmed/23076896?tool=bestpractice.com
[41]Cruz F, Dambros M, Naber KG, et al. Recurrent urinary tract infections: Uro-Vaxom, a new alternative. Eur Urol Suppl. 2009;8:762-8.[42]Naber KG, Cho YH, Matsumoto T, et al. Immunoactive prophylaxis of recurrent urinary tract infections: a meta-analysis. Int J Antimicrob Agents. 2009 Feb;33(2):111-9.
http://www.ncbi.nlm.nih.gov/pubmed/18963856?tool=bestpractice.com