Evitar o tabaco e bebidas alcoólicas pode reduzir o risco de carcinoma de células escamosas esofágico (CCEO).[80]National Cancer Institute. Esophageal cancer prevention (PDQ®) - health professional version. Sep 2022 [internet publication].
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Dietas ricas em vegetais crucíferos (repolho, brócolis, couve-flor), vegetais verdes e amarelos e frutas estão associadas a um risco mais baixo de carcinoma de células escamosas esofágico (CCEE).[74]Vingeliene S, Chan DSM, Vieira AR, et al. An update of the WCRF/AICR systematic literature review and meta-analysis on dietary and anthropometric factors and esophageal cancer risk. Ann Oncol. 2017 Oct 1;28(10):2409-19.
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Há evidências que sugerem efeitos quimiopreventivos da aspirina e de anti-inflamatórios não esteroidais.[80]National Cancer Institute. Esophageal cancer prevention (PDQ®) - health professional version. Sep 2022 [internet publication].
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Os riscos de danos podem impedir o uso rotineiro desses agentes.[83]Snider EJ, Kaz AM, Inadomi JM, et al. Chemoprevention of esophageal adenocarcinoma. Gastroenterol Rep (Oxf). 2020 Aug;8(4):253-60.
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As estatinas podem reduzir o risco do desenvolvimento de adenocarcinoma esofágico (ACE); são necessários dados adicionais.[84]Alexandre L, Clark AB, Cheong E, et al. Systematic review: potential preventive effects of statins against oesophageal adenocarcinoma. Aliment Pharmacol Ther. 2012 Aug;36(4):301-11.
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Não se sabe se a eliminação do refluxo gastroesofágico por meios cirúrgicos ou clínicos reduz o risco de ACE.[80]National Cancer Institute. Esophageal cancer prevention (PDQ®) - health professional version. Sep 2022 [internet publication].
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