As estimativas de prevalência de IVC variam muito, dependendo da região geográfica e dos critérios de diagnóstico.[3]Beebe-Dimmer JL, Pfeifer JR, Engle JS, et al. The epidemiology of chronic venous insufficiency and varicose veins. Ann Epidemiol. 2005 Mar;15(3):175-84.
http://www.ncbi.nlm.nih.gov/pubmed/15723761?tool=bestpractice.com
[4]Salim S, Machin M, Patterson BO, et al. Global epidemiology of chronic venous disease: a systematic review with pooled prevalence analysis. Ann Surg. 2021 Dec 1;274(6):971-6.
http://www.ncbi.nlm.nih.gov/pubmed/33214466?tool=bestpractice.com
[5]Rabe E, Régnier C, Goron F, et al. The prevalence, disease characteristics and treatment of chronic venous disease: an international web-based survey. J Comp Eff Res. 2020 Dec;9(17):1205-18.
https://becarispublishing.com/doi/10.2217/cer-2020-0158
http://www.ncbi.nlm.nih.gov/pubmed/33079592?tool=bestpractice.com
[6]Homs-Romero E, Romero-Collado A, Verdú J, et al. Validity of chronic venous disease diagnoses and epidemiology using validated electronic health records from primary care: a real-world data analysis. J Nurs Scholarsh. 2021 May;53(3):296-305.
http://www.ncbi.nlm.nih.gov/pubmed/33638608?tool=bestpractice.com
[7]Cesarone MR, Belcaro G, Nicolaides AN, et al. 'Real' epidemiology of varicose veins and chronic venous diseases: the San Valentino Vascular Screening Project. Angiology. 2002 Mar-Apr;53(2):119-30.
http://www.ncbi.nlm.nih.gov/pubmed/11952101?tool=bestpractice.com
[8]Evans CJ, Fowkes FG, Ruckley CV, et al. Prevalence of varicose veins and chronic venous insufficiency in men and women in the general population: Edinburgh Vein Study. J Epidemiol Community Health. 1999 Mar;53(3):149-53.
https://jech.bmj.com/content/jech/53/3/149.full.pdf
http://www.ncbi.nlm.nih.gov/pubmed/10396491?tool=bestpractice.com
Em uma revisão sistemática, a prevalência combinada estimada foi de 8% para classe C3 (edema), 4% para classe C4 (alterações cutâneas secundárias à IVC), 1% para classe C5 (úlcera venosa cicatrizada) e 0.42% para classe C6 (úlcera venosa ativa).[4]Salim S, Machin M, Patterson BO, et al. Global epidemiology of chronic venous disease: a systematic review with pooled prevalence analysis. Ann Surg. 2021 Dec 1;274(6):971-6.
http://www.ncbi.nlm.nih.gov/pubmed/33214466?tool=bestpractice.com
Os fatores de risco comuns para doença venosa crônica, e IVC, são idade avançada, sexo feminino, obesidade, história familiar e ocupações com posição ortostática prolongada.