Resumo
Definição
História e exame físico
Principais fatores diagnósticos
- presença de fatores de risco
- taquicardia
- hipertensão
- hipertermia
- agitação
- midríase
- diaforese
Fatores de risco
- temperatura ambiente elevada
- pobreza
- body packing de cocaína
- sexo masculino
- deficiência de colinesterase plasmática
- idade entre 18-25 anos
- história de uso de cocaína
- uso concomitante de outros simpatomiméticos
Investigações diagnósticas
Primeiras investigações a serem solicitadas
- eletrocardiograma (ECG)
- glicose sérica à beira do leito
- creatinina sérica
- ureia
- creatina fosfoquinase sérica (CPK)
- troponina sérica
- radiografia torácica
- tomografia computadorizada (TC) cranioencefálica
Investigações a serem consideradas
- teste de cocaína na urina
- tomografia computadorizada (TC) de abdome e pelve
Algoritmo de tratamento
Colaboradores
Autores
Andrew Stolbach, MD, MPH
Attending Physician
Johns Hopkins Hospital
Baltimore
MD
Declarações
AS has been reimbursed by Peerview Education for delivering educational lectures unrelated to this topic; for expert testimony in unrelated toxicology topics; and by UpToDate for writing articles on other toxicology topics.
Revisores
Janice Zimmerman, MD
Head
Critical Care Division
The Methodist Hospital
Houston
TX
Declarações
JZ declares that she has no competing interests. JZ is the author of an article cited in this text, but the article was not included in the text at the time of her peer review.
Alison Jones, MD, FRCPE, FiBIOL, FRCP, FRACP
Dean
School of Medicine
Campbelltown Campus
University of Western Sydney
Australia
Declarações
AJ declares that she has no competing interests.
Andrew Parfitt, MBBS, FFAEM
Clinical Director
Acute Medicine
Associate Medical Director
Consultant Emergency Medicine
Guy's and St Thomas' NHS Foundation Trust
Clinical Lead and Consultant
Accident Emergency Medicine
St Thomas' Hospital
London
UK
Declarações
AP declares that he has no competing interests.
Referências
Principais artigos
Lavonas EJ, Akpunonu PD, Arens AM, et al. 2023 American Heart Association focused update on the management of patients with cardiac arrest or life-threatening toxicity due to poisoning: an update to the American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation. 2023 Oct 17;148(16):e149-84.Texto completo Resumo
Royal College of Emergency Medicine. Management of suspected internal drug trafficker (SIDT). Dec 2020 [internet publication].Texto completo
Panchal AR, Bartos JA, Cabañas JG, et al. Part 3: adult basic and advanced life support: 2020 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation. 2020 Oct 20;142(16_suppl_2):S366-468.Texto completo
Smollin CG, Hoffman RS. Chapter 75: Cocaine. In: Nelson LS, Howland MA, Lewin NA, et al, eds. Goldfrank's toxicologic emergencies, 11th ed. New York, NY: McGraw-Hill Education; 2019.
Artigos de referência
Uma lista completa das fontes referenciadas neste tópico está disponível aqui.
Diretrizes
- Mental Health Gap Action Programme (mhGAP) guideline for mental, neurological and substance use disorders
- 2023 American Heart Association focused update on the management of patients with cardiac arrest or life-threatening toxicity due to poisoning: an update to the American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care
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