Referências
Principais artigos
Brophy GM, Bell R, Claassen J, et al; Neurocritical Care Society Status Epilepticus Guideline Writing Committee. Guidelines for the evaluation and management of status epilepticus. Neurocrit Care. 2012 Aug;17(1):3-23. Resumo
Glauser T, Shinnar S, Gloss D. Evidence-based guideline: treatment of convulsive status epilepticus in children and adults: report of the Guideline Committee of the American Epilepsy Society. Epilepsy Curr. 2016 Jan-Feb;16(1):48-61.Texto completo Resumo
National Institute for Health and Care Excellence. Epilepsies in children, young people and adults. Jan 2025 [internet publication].Texto completo
Artigos de referência
1. Lowenstein DH, Bleck T, Macdonald RL. It's time to revise the definition of status epilepticus. Epilepsia. 1999 Jan;40(1):120-2. Resumo
2. Brophy GM, Bell R, Claassen J, et al; Neurocritical Care Society Status Epilepticus Guideline Writing Committee. Guidelines for the evaluation and management of status epilepticus. Neurocrit Care. 2012 Aug;17(1):3-23. Resumo
3. Fisher RS, Cross JH, French JA, et al. Operational classification of seizure types by the International League Against Epilepsy: position paper of the ILAE Commission for Classification and Terminology. Epilepsia. 2017 Apr;58(4):522-30.Texto completo Resumo
4. Ochoa JG, Dougherty M, Papanastassiou A, et al. Treatment of super-refractory status epilepticus: a review. Epilepsy Curr. 2021 Mar 10;21(6):1535759721999670.Texto completo Resumo
5. Wickstrom R, Taraschenko O, Dilena R, et al. International consensus recommendations for management of new onset refractory status epilepticus (NORSE) including febrile infection-related epilepsy syndrome (FIRES): summary and clinical tools. Epilepsia. 2022 Aug 11;63(11):2827-39.Texto completo Resumo
6. Tharmaraja T, Ho JSY, Neligan A, et al. The etiology and mortality of new-onset refractory status epilepticus (NORSE) in adults: a systematic review and meta-analysis. Epilepsia. 2023 May;64(5):1113-24. Resumo
7. Trinka E, Cock H, Hesdorffer D, et al. A definition and classification of status epilepticus - report of the ILAE Task Force on Classification of Status Epilepticus. Epilepsia. 2015 Oct;56(10):1515-23. Resumo
8. Dham BS, Hunter K, Rincon F. The epidemiology of status epilepticus in the United States. Neurocrit Care. 2014 Jun;20(3):476-83. Resumo
9. DeLorenzo RJ, Hauser WA, Towne AR, et al. A prospective, population-based epidemiologic study of status epilepticus in Richmond, Virginia. Neurology. 1996 Apr;46(4):1029-35. Resumo
10. Shorvon S, Sen A. What is status epilepticus and what do we know about its epidemiology? Seizure. 2020 Feb;75:131-6.Texto completo Resumo
11. Hauser WA. Status epilepticus: epidemiologic considerations. Neurology. 1990 May;40(5 suppl 2):S9-13. Resumo
12. American Academy of Neurology. Antiseizure medication withdrawal in seizure-free patients practice advisory update: practice advisory, December 2021. Feb 2025 [internet publication].Texto completo
13. Pellock JM. Overview: definitions and classifications of seizure emergencies. J Child Neurol. 2007 May;22(5 suppl):S9-13. Resumo
14. Craig DP, Mitchell TN, Thomas RH. A tiered strategy for investigating status epilepticus. Seizure. 2020 Feb;75:165-73.Texto completo Resumo
15. Coeytaux A, Jallon P, Galobardes B, et al. Incidence of status epilepticus in French-speaking Switzerland: (EPISTAR). Neurology. 2000 Sep 12;55(5):693-7. Resumo
16. Vooturi S, Jayalakshmi S, Sahu S, et al. Prognosis and predictors of outcome of refractory generalized convulsive status epilepticus in adults treated in neurointensive care unit. Clin Neurol Neurosurg. 2014 Nov;126:7-10. Resumo
17. Bien CG, Granata T, Antozzi C, et al. Pathogenesis, diagnosis and treatment of Rasmussen encephalitis: a European consensus statement. Brain. 2005 Mar;128(pt 3):454-71. Resumo
18. Howell KB, Katanyuwong K, Mackay MT, et al. Long-term follow-up of febrile infection-related epilepsy syndrome. Epilepsia. 2012 Jan;53(1):101-10. Resumo
19. Swor D, Juneja P, Constantine C, et al. Management of status epilepticus in pregnancy: a clinician survey. Neurol Res Pract. 2024 Jan 18;6(1):3.Texto completo Resumo
20. Rajiv KR, Radhakrishnan A. Status epilepticus in pregnancy: etiology, management, and clinical outcomes. Epilepsy Behav. 2017 Nov;76:114-9. Resumo
21. Lowenstein DH, Alldredge BK. Status epilepticus. N Engl J Med. 1998 Apr 2;338(14):970-6. Resumo
22. Betjemann JP, Lowenstein DH. Status epilepticus in adults. Lancet Neurol. 2015 Jun;14(6):615-24. Resumo
23. Chen JW, Naylor DE, Wasterlain CG. Advances in the pathophysiology of status epilepticus. Acta Neurol Scand Suppl. 2007;186:7-15. Resumo
24. Naylor DE, Liu H, Wasterlain CG. Trafficking of GABA(A) receptors, loss of inhibition, and a mechanism for pharmacoresistance in status epilepticus. J Neurosci. 2005 Aug 24;25(34):7724-33.Texto completo Resumo
25. Goodkin HP, Sun C, Yeh JL, et al. GABA(A) receptor internalization during seizures. Epilepsia. 2007;48(suppl 5):109-13. Resumo
26. Naylor DE, Liu H, Niquet J, et al. Rapid surface accumulation of NMDA receptors increases glutamatergic excitation during status epilepticus. Neurobiol Dis. 2013 Jun;54:225-38.Texto completo Resumo
27. Jones DM, Esmaeil N, Maren S, et al. Characterization of pharmacoresistance to benzodiazepines in the rat Li-pilocarpine model of status epilepticus. Epilepsy Res. 2002 Aug;50(3):301-12. Resumo
28. Kapur J, Macdonald RL. Rapid seizure-induced reduction of benzodiazepine and Zn2+ sensitivity of hippocampal dentate granule cell GABAA receptors. J Neurosci. 1997 Oct 1;17(19):7532-40.Texto completo Resumo
29. Meldrum BS, Vigouroux RA, Rage P, et al. Hippocampal lesions produced by prolonged seizures in paralyzed artificially ventilated baboons. Experientia. 1973 May 15;29(5):561-3. Resumo
30. Alldredge BK, Lowenstein DH. Status epilepticus related to alcohol abuse. Epilepsia. 1993 Nov-Dec;34(6):1033-7. Resumo
31. Trinka E, Höfler J, Zerbs A. Causes of status epilepticus. Epilepsia. 2012 Sep;53(suppl 4):127-38. Resumo
32. Shinnar S. Who is at risk for prolonged seizures? J Child Neurol. 2007 May;22(5 suppl):S14-20. Resumo
33. De Stefano P, Kaplan PW, Quintard H, et al. Nonconvulsive status epilepticus following cardiac arrest: overlooked, untreated and misjudged. J Neurol. 2023 Jan;270(1):130-8.Texto completo Resumo
34. Crawshaw AA, Cock HR. Medical management of status epilepticus: emergency room to intensive care unit. Seizure. 2020 Feb;75:145-52.Texto completo Resumo
35. Hesdorffer DC, Logroscino G, Cascino G, et al. Incidence of status epilepticus in Rochester, Minnesota, 1965-1984. Neurology. 1998 Mar;50(3):735-41. Resumo
36. Glauser T, Shinnar S, Gloss D. Evidence-based guideline: treatment of convulsive status epilepticus in children and adults: report of the Guideline Committee of the American Epilepsy Society. Epilepsy Curr. 2016 Jan-Feb;16(1):48-61.Texto completo Resumo
37. Herman ST, Abend NS, Bleck TP, et al. Consensus statement on continuous EEG in critically ill adults and children, part I: indications. J Clin Neurophysiol. 2015 Apr;32(2):87-95.Texto completo Resumo
38. Teramoto K, Horiguchi S, Wakitani F, et al. Effects of styrene on wheel-running and ambulatory activities in mice. J Toxicol Sci. 1988 May;13(2):133-9.Texto completo Resumo
39. National Institute for Health and Care Excellence. Epilepsies in children, young people and adults. Jan 2025 [internet publication].Texto completo
40. Krumholz A. Epidemiology and evidence for morbidity of nonconvulsive status epilepticus. J Clin Neurophysiol. 1999 Jul;16(4):314-22. Resumo
41. Sutton F, Barca D, Komoltsev I, et al. Testing blood and CSF in people with epilepsy: a practical guide. Epileptic Disord. 2020 Aug 1;22(4):381-98.Texto completo Resumo
42. Neligan A, Shorvon SD. Prognostic factors, morbidity and mortality in tonic-clonic status epilepticus: a review. Epilepsy Res. 2011 Jan;93(1):1-10. Resumo
43. Cascino GD. Generalized convulsive status epilepticus. Mayo Clin Proc. 1996 Aug;71(8):787-92. Resumo
44. Treiman DM. Treatment of convulsive status epilepticus. Int Rev Neurobiol. 2007 Sep 17;339(12):792-8. Resumo
45. Glatstein M, Carbell G, Scolnik D, et al. Pyridoxine for the treatment of isoniazid-induced seizures in intentional ingestions: the experience of a national poison center. Am J Emerg Med. 2018 Oct;36(10):1775-8. Resumo
46. Kalviainen R, Eriksson K, Parviainen I. Refractory generalised convulsive status epilepticus: a guide to treatment. CNS Drugs. 2005;19(9):759-68. Resumo
47. Treiman DM, Meyers PD, Walton NY, et al; Veterans Affairs Status Epilepticus Cooperative Study Group. A comparison of four treatments for generalized convulsive status epilepticus. N Engl J Med. 1998 Sep 17;339(12):792-8.Texto completo Resumo
48. Silbergleit R, Durkalski V, Lowenstein D, et al. Intramuscular versus intravenous therapy for prehospital status epilepticus. N Engl J Med. 2012 Feb 16;366(7):591-600.Texto completo Resumo
49. Wheless JW, Clarke DF, Arzimanoglou A, et al. Treatment of pediatric epilepsy: European expert opinion, 2007. Epileptic Disord. 2007 Dec;9(4):353-412. Resumo
50. Gaínza-Lein M, Sánchez Fernández I, Jackson M, et al. Association of time to treatment with short-term outcomes for pediatric patients with refractory convulsive status epilepticus. JAMA Neurol. 2018 Apr 1;75(4):410-8.Texto completo Resumo
51. Osorio I, Reed RC. Treatment of refractory generalized tonic-clonic status epilepticus with pentobarbital anesthesia after high-dose phenytoin. Epilepsia. 1989 Jul-Aug;30(4):464-71. Resumo
52. Kapur J, Elm J, Chamberlain JM, et al. Randomized trial of three anticonvulsant medications for status epilepticus. N Engl J Med. 2019 Nov 28;381(22):2103-13.Texto completo Resumo
53. Chamberlain JM, Kapur J, Shinnar S, et al. Efficacy of levetiracetam, fosphenytoin, and valproate for established status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomised controlled trial. Lancet. 2020 Apr 11;395(10231):1217-24.Texto completo Resumo
54. Lyttle MD, Rainford NEA, Gamble C, et al. Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial. Lancet. 2019 May 25;393(10186):2125-34.Texto completo Resumo
55. Dalziel SR, Borland ML, Furyk J, et al. Levetiracetam versus phenytoin for second-line treatment of convulsive status epilepticus in children (ConSEPT): an open-label, multicentre, randomised controlled trial. Lancet. 2019 May 25;393(10186):2135-45. Resumo
56. Trinka E, Höfler J, Leitinger M, et al. Pharmacotherapy for status epilepticus. Drugs. 2015 Sep;75(13):1499-521.Texto completo Resumo
57. Vasile B, Rasulo F, Candiani A, et al. The pathophysiology of propofol infusion syndrome: a simple name for a complex syndrome. Intensive Care Med. 2003 Sep;29(9):1417-25. Resumo
58. Parviainen I, Uusaro A, Kalviainen R, et al. High-dose thiopental in the treatment of refractory status epilepticus in intensive care unit. Neurology. 2002 Oct 22;59(8):1249-51. Resumo
59. Woodward MR, Kardon A, Manners J, et al. Comparison of induction agents for rapid sequence intubation in refractory status epilepticus: a single-center retrospective analysis. Epilepsy Behav Rep. 2024;25:100645.Texto completo Resumo
60. Shorvon S, Ferlisi M. The treatment of super-refractory status epilepticus: a critical review of available therapies and a clinical treatment protocol. Brain. 2011 Oct;134(pt 10):2802-18. Resumo
61. Cornwall CD, Krøigård T, Kristensen JSS, et al. Outcomes and treatment approaches for super-refractory status epilepticus: a systematic review and meta-analysis. JAMA Neurol. 2023 Jul 31;80(9):959-68.Texto completo Resumo
62. Medicines and Healthcare products Regulatory Agency. Antiepileptic drugs in pregnancy: updated advice following comprehensive safety review. Jan 2021 [internet publication].Texto completo
63. Pack AM, Oskoui M, Williams Roberson S, et al. Teratogenesis, perinatal, and neurodevelopmental outcomes after in utero exposure to antiseizure medication: practice guideline from the AAN, AES, and SMFM. Neurology. 2024 Jun;102(11):e209279.Texto completo Resumo
64. Battino D, Tomson T, Bonizzoni E, et al. Risk of major congenital malformations and exposure to antiseizure medication monotherapy. JAMA Neurol. 2024 May 1;81(5):481-9.Texto completo Resumo
65. Bromley R, Adab N, Bluett-Duncan M, et al. Monotherapy treatment of epilepsy in pregnancy: congenital malformation outcomes in the child. Cochrane Database Syst Rev. 2023 Aug 29;8(8):CD010224.Texto completo Resumo
66. American Diabetes Association Professional Practice Committee. 6. Glycemic goals and hypoglycemia: standards of care in diabetes-2025. Diabetes Care. 2025 Jan 1;48(1 suppl 1):S128-45.Texto completo Resumo
67. Towne AR, Garnett LK, Waterhouse EJ, et al. The use of topiramate in refractory status epilepticus. Neurology. 2003 Jan 28;60(2):332-4. Resumo
68. Welling LC, Rabelo NN, Yoshikawa MH, et al. Efficacy of topiramate as an add-on therapy in patients with refractory status epilepticus: a short systematic review. [in por]. Rev Bras Ter Intensiva. 2021 Oct 25;33(3):440-4.Texto completo Resumo
69. Inokuchi R, Ohashi-Fukuda N, Nakamura K, et al. Comparison of intranasal and intravenous diazepam on status epilepticus in stroke patients: a retrospective cohort study. Medicine (Baltimore). 2015 Feb;94(7):e555.Texto completo Resumo
70. Pieribone VA, Tsai J, Soufflet C, et al. Clinical evaluation of ganaxolone in pediatric and adolescent patients with refractory epilepsy. Epilepsia. 2007 Oct;48(10):1870-4. Resumo
71. Vaitkevicius H, Ramsay RE, Swisher CB, et al. Intravenous ganaxolone for the treatment of refractory status epilepticus: results from an open-label, dose-finding, phase 2 trial. Epilepsia. 2022 Sep;63(9):2381-91.Texto completo Resumo
72. Rosenthal ES, Claassen J, Wainwright MS, et al. Brexanolone as adjunctive therapy in super-refractory status epilepticus. Ann Neurol. 2017 Sep;82(3):342-52.Texto completo Resumo
73. Thakur KT, Probasco JC, Hocker SE, et al. Ketogenic diet for adults in super-refractory status epilepticus. Neurology. 2014 Feb 25;82(8):665-70.Texto completo Resumo
74. Cervenka MC, Hocker S, Koenig M, et al. Phase I/II multicenter ketogenic diet study for adult superrefractory status epilepticus. Neurology. 2017 Mar 7;88(10):938-43.Texto completo Resumo
75. Appavu B, Vanatta L, Condie J, et al. Ketogenic diet treatment for pediatric super-refractory status epilepticus. Seizure. 2016 Oct;41:62-5.Texto completo Resumo
76. Lee K, Klein P, Dongre P, et al. Intravenous brivaracetam in the management of acute seizures in the hospital setting: a scoping review. J Intensive Care Med. 2022 Sep;37(9):1133-45.Texto completo Resumo
77. Klein P, Schiemann J, Sperling MR, et al. A randomized, double-blind, placebo-controlled, multicenter, parallel-group study to evaluate the efficacy and safety of adjunctive brivaracetam in adult patients with uncontrolled partial-onset seizures. Epilepsia. 2015 Dec;56(12):1890-8.Texto completo Resumo
78. Ryvlin P, Werhahn KJ, Blaszczyk B, et al. Adjunctive brivaracetam in adults with uncontrolled focal epilepsy: results from a double-blind, randomized, placebo-controlled trial. Epilepsia. 2014 Jan;55(1):47-56.Texto completo Resumo
79. Biton V, Berkovic SF, Abou-Khalil B, et al. Brivaracetam as adjunctive treatment for uncontrolled partial epilepsy in adults: a phase III randomized, double-blind, placebo-controlled trial. Epilepsia. 2014 Jan;55(1):57-66.Texto completo Resumo
80. Szaflarski JP, Sadek A, Greve B, et al. Randomized open-label trial of intravenous brivaracetam versus lorazepam for acute treatment of increased seizure activity. Epilepsy Behav. 2020 Aug;109:107127.Texto completo Resumo
81. Orlandi N, Bartolini E, Audenino D, et al. Intravenous brivaracetam in status epilepticus: a multicentric retrospective study in Italy. Seizure. 2021 Mar;86:70-6.Texto completo Resumo
82. Lattanzi S, Chiesa V, Di Gennaro G, et al. Brivaracetam use in clinical practice: a delphi consensus on its role as first add-on therapy in focal epilepsy and beyond. Neurol Sci. 2024 Sep;45(9):4519-27.Texto completo Resumo
83. Neville BG, Chin RF, Scott RC. Childhood convulsive status epilepticus: epidemiology, management and outcome. Acta Neurol Scand. 2007 Apr;115(4 suppl):S21-4. Resumo
84. Koubeissi M, Alshekhlee A. In-hospital mortality of generalized convulsive status epilepticus: a large US sample. Neurology. 2007 Aug 28;69(9):886-93. Resumo
85. Neligan A, Noyce AJ, Gosavi TD, et al. Change in mortality of generalized convulsive status epilepticus in high-income countries over time: a systematic review and meta-analysis. JAMA Neurol. 2019 May 28;76(8):897-905.Texto completo Resumo
86. Neligan A, Shorvon SD. Frequency and prognosis of convulsive status epilepticus of different causes: a systematic review. Arch Neurol. 2010 Aug;67(8):931-40. Resumo
87. Migdady I, Rosenthal ES, Cock HR. Management of status epilepticus: a narrative review. Anaesthesia. 2022 Jan;77(suppl 1):78-91.Texto completo Resumo
88. Yaffe K, Lowenstein DH. Prognostic factors of pentobarbital therapy for refractory generalized status epilepticus. Neurology. 1993 May;43(5):895-900. Resumo
89. Jambaque I, Hertz-Pannier L, Mikaeloff Y, et al. Severe memory impairment in a child with bihippocampal injury after status epilepticus. Dev Med Child Neurol. 2006 Mar;48(3):223-6.Texto completo Resumo
90. Hawkes MA, Hocker SE. Systemic complications following status epilepticus. Curr Neurol Neurosci Rep. 2018 Feb 7;18(2):7. Resumo
91. Hocker S, Nagarajan E, Rabinstein AA, et al. Progressive brain atrophy in super-refractory status epilepticus. JAMA Neurol. 2016 Oct 1;73(10):1201-7.Texto completo Resumo
92. Gramstad A, Power KN, Engelsen BA. Neuropsychological performance 1 year after status epilepticus in adults. Arch Clin Neuropsychol. 2021 Apr 21;36(3):329-38. Resumo
93. Rodrigo-Gisbert M, Gómez-Dabó L, Quintana M, et al. Prediction of long-term unprovoked seizures after status epilepticus. Epilepsia. 2023 Sep;64(9):2399-408. Resumo
O uso deste conteúdo está sujeito ao nosso aviso legal