Patients’ preferences and goals should be discussed. Likely adherence with a daily controller should be considered when deciding between initial treatments. Also consider patient concerns about inhaler choice, including environmental issues (see
Asthma + Lung UK: inhaler choices
Opens in new window).[204]Ten Have P, van Hal P, Wichers I, et al. Turning green: the impact of changing to more eco-friendly respiratory healthcare - a carbon and cost analysis of Dutch prescription data. BMJ Open. 2022 Jun 14;12(6):e055546.
http://www.ncbi.nlm.nih.gov/pubmed/35701064?tool=bestpractice.com
The patient should be able to use their inhaler device correctly, and a follow-up appointment should be arranged.[52]Global Initiative for Asthma. 2024 global strategy for asthma management and prevention. May 2024 [internet publication].
https://ginasthma.org/wp-content/uploads/2024/05/GINA-2024-Strategy-Report-24_05_22_WMS.pdf
It is essential to inform the patient that effective home management of symptoms greatly improves outcome. Self-monitoring on a daily basis should be encouraged by, for example, checking and recording peak expiratory flow (PEF) using the PEF meter. When the patient discusses these results with his or her physician, subsequent adjustment of medications can be made. It should be emphasized that attending follow-up is essential for a long and healthy life with asthma.
Poor adherence is often driven by a lack of disease education (e.g., not knowing when to take medication and a lack of belief that medication will improve asthma control) and should be addressed proactively.[205]Riley IL, Jackson B, Crabtree D, et al. A scoping review of international barriers to asthma medication adherence mapped to the theoretical domains framework. J Allergy Clin Immunol Pract. 2021 Jan;9(1):410-8.e4.
http://www.ncbi.nlm.nih.gov/pubmed/32861047?tool=bestpractice.com
Strategies to improve inhaler adherence include text/audiovisual message reminders, written action plans, and motivational interviewing.[206]van de Hei SJ, Dierick BJH, Aarts JEP, et al. Personalized medication adherence management in asthma and chronic obstructive pulmonary disease: a review of effective interventions and development of a practical adherence toolkit. J Allergy Clin Immunol Pract. 2021 Nov;9(11):3979-94.
https://www.doi.org/10.1016/j.jaip.2021.05.025
http://www.ncbi.nlm.nih.gov/pubmed/34111571?tool=bestpractice.com
Enhanced support may be required for patients transitioning into adulthood, as some studies report reduced adherence in patients >18 years of age.[207]Murphy J, McSharry J, Hynes L, et al. Prevalence and predictors of adherence to inhaled corticosteroids in young adults (15-30 years) with asthma: a systematic review and meta-analysis. J Asthma. 2021 May;58(5):683-705.
http://www.ncbi.nlm.nih.gov/pubmed/31906744?tool=bestpractice.com
Telemedicine appears to be effective in improving asthma control and quality of life in adults with asthma.[208]Chongmelaxme B, Lee S, Dhippayom T, et al. The effects of telemedicine on asthma control and patients' quality of life in adults: a systematic review and meta-analysis. J Allergy Clin Immunol Pract. 2019 Jan;7(1):199-216.
http://www.ncbi.nlm.nih.gov/pubmed/30055283?tool=bestpractice.com
eHealth interventions are effective in improving adherence to inhaled corticosteroid, particularly mobile device-based studies that include audiovisual and text message reminders.[209]Jeminiwa R, Hohmann L, Qian J, et al. Impact of eHealth on medication adherence among patients with asthma: a systematic review and meta-analysis. Respir Med. 2019 Mar;149:59-68.
https://www.resmedjournal.com/article/S0954-6111(19)30047-2/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/30803887?tool=bestpractice.com
Digital health technology that includes interactive features, such as daily diary entries, is associated with increased asthma control; the same is true for multidimensional interventions that combine several different types of digital health technology.[210]Unni E, Gabriel S, Ariely R. A review of the use and effectiveness of digital health technologies in patients with asthma. Ann Allergy Asthma Immunol. 2018 Dec;121(6):680-91.
https://www.annallergy.org/article/S1081-1206(18)31314-0/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/30352288?tool=bestpractice.com
Pharmacist-led interventions can also improve inhaler technique and medication adherence in adults with asthma.[211]Mes MA, Katzer CB, Chan AHY, et al. Pharmacists and medication adherence in asthma: a systematic review and meta-analysis. Eur Respir J. 2018 Aug 23;52(2):1800485.
https://erj.ersjournals.com/content/52/2/1800485.long
http://www.ncbi.nlm.nih.gov/pubmed/29976652?tool=bestpractice.com
[212]Jia X, Zhou S, Luo D, et al. Effect of pharmacist-led interventions on medication adherence and inhalation technique in adult patients with asthma or COPD: A systematic review and meta-analysis. J Clin Pharm Ther. 2020 Oct;45(5):904-17.
https://www.doi.org/10.1111/jcpt.13126
http://www.ncbi.nlm.nih.gov/pubmed/32107837?tool=bestpractice.com
The impact of home visits has been shown to be beneficial in children with asthma; however, there is currently insufficient evidence to recommend this intervention in adult patients.[213]Muneswarao J, Hassali MA, Ibrahim B, et al. Effectiveness of home visits in adult patients with asthma: a systematic review of randomized controlled trials. J Allergy Clin Immunol Pract. 2020 Oct;8(9):3036-55.
http://www.ncbi.nlm.nih.gov/pubmed/32502547?tool=bestpractice.com
Environmental control strategies should also be discussed, including identifying and eliminating home and work/school exposure (indoor or outdoor) to allergens that can cause or worsen asthma, including house-dust mites, animals, cigarette smoke and other respiratory irritants, chemicals, and pollens and grasses.[52]Global Initiative for Asthma. 2024 global strategy for asthma management and prevention. May 2024 [internet publication].
https://ginasthma.org/wp-content/uploads/2024/05/GINA-2024-Strategy-Report-24_05_22_WMS.pdf
International guidelines vary in their recommendations regarding allergen mitigation, so local guidance should be consulted to inform the discussion with the patient. For example, the 2020 US asthma guidelines conditionally recommend a multicomponent, allergen-specific mitigation intervention in people with asthma who have symptoms related to identified indoor allergens, confirmed by history or allergy testing.[62]Expert Panel Working Group of the National Heart, Lung, and Blood Institute (NHLBI) administered and coordinated National Asthma Education and Prevention Program Coordinating Committee (NAEPPCC); Cloutier MM, Baptist AP, Blake KV, et al. 2020 focused updates to the asthma management guidelines: a report from the National Asthma Education and Prevention Program Coordinating Committee Expert Panel Working Group. J Allergy Clin Immunol. 2020 Dec;146(6):1217-70.
https://www.doi.org/10.1016/j.jaci.2020.10.003
http://www.ncbi.nlm.nih.gov/pubmed/33280709?tool=bestpractice.com
Occupational exposure should also be discussed and assessed. Foods to which the patient is sensitive should be identified and avoided (e.g., foods containing sulfites).[52]Global Initiative for Asthma. 2024 global strategy for asthma management and prevention. May 2024 [internet publication].
https://ginasthma.org/wp-content/uploads/2024/05/GINA-2024-Strategy-Report-24_05_22_WMS.pdf
Patients should be counseled about avoiding specific drugs (e.g., aspirin and nonsteroidal anti-inflammatory drugs, beta-blockers) where necessary, immunization (e.g., influenza), smoking cessation (if applicable), treatment of comorbidities (e.g., gastroesophageal reflux, obesity, infections), correct use of medications and delivery devices, self-monitoring of symptom control, and the importance of an asthma action plan.[52]Global Initiative for Asthma. 2024 global strategy for asthma management and prevention. May 2024 [internet publication].
https://ginasthma.org/wp-content/uploads/2024/05/GINA-2024-Strategy-Report-24_05_22_WMS.pdf
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Patients with asthma are at increased risk of depression and anxiety and these comorbidities may worsen asthma control. A mental health assessment should be arranged for those presenting with psychiatric symptoms.[52]Global Initiative for Asthma. 2024 global strategy for asthma management and prevention. May 2024 [internet publication].
https://ginasthma.org/wp-content/uploads/2024/05/GINA-2024-Strategy-Report-24_05_22_WMS.pdf
Patients with asthma also have a significantly increased risk of suicidal ideation, suicide attempts, and suicide mortality.[214]Zhang Y, Cheng J, Li Y, et al. Suicidality among patients with asthma: a systematic review and meta-analysis. J Affect Disord. 2019 Sep 1;256:594-603.
http://www.ncbi.nlm.nih.gov/pubmed/31299440?tool=bestpractice.com