Eosinophilic oesophagitis

Eosinophilic oesophagitis (EoO) is a chronic condition. Monitoring can vary depending on the treatment and the individual features of the patient. Assessment of symptomatic, endoscopic, and histological outcomes is recommended to evaluate response to treatment.[3]Dellon ES, Muir AB, Katzka DA, et al. ACG clinical guideline: diagnosis and management of eosinophilic esophagitis. Am J Gastroenterol. 2025 Jan 1;120(1):31-59. https://journals.lww.com/ajg/fulltext/2025/01000/acg_clinical_guideline__diagnosis_and_management.16.aspx http://www.ncbi.nlm.nih.gov/pubmed/39745304?tool=bestpractice.com [82]Aceves SS, Alexander JA, Baron TH, et al. Endoscopic approach to eosinophilic esophagitis: American Society for Gastrointestinal Endoscopy consensus conference. Gastrointest Endosc. 2022 Oct;96(4):576-92.e1. https://www.giejournal.org/article/S0016-5107(22)01725-4/fulltext http://www.ncbi.nlm.nih.gov/pubmed/35965102?tool=bestpractice.com ​ Repeat oesophagogastroduodenoscopy (OGD) to assess endoscopic and histological disease activity is recommended after initiating or changing treatment, or with a change or worsening in clinical status.​​​​[3]Dellon ES, Muir AB, Katzka DA, et al. ACG clinical guideline: diagnosis and management of eosinophilic esophagitis. Am J Gastroenterol. 2025 Jan 1;120(1):31-59. https://journals.lww.com/ajg/fulltext/2025/01000/acg_clinical_guideline__diagnosis_and_management.16.aspx http://www.ncbi.nlm.nih.gov/pubmed/39745304?tool=bestpractice.com ​​[27]Dellon ES, Liacouras CA. Advances in clinical management of eosinophilic esophagitis. Gastroenterology. 2014 Dec;147(6):1238-54. https://www.gastrojournal.org/article/S0016-5085(14)00980-9/fulltext http://www.ncbi.nlm.nih.gov/pubmed/25109885?tool=bestpractice.com ​

Symptoms only modestly correlate with other measures of disease activity.[178]Safroneeva E, Straumann A, Coslovsky M, et al. Symptoms have modest accuracy in detecting endoscopic and histologic remission in adults with eosinophilic esophagitis. Gastroenterology. 2016 Mar;150(3):581-90. https://www.gastrojournal.org/article/S0016-5085(15)01621-2/fulltext http://www.ncbi.nlm.nih.gov/pubmed/26584601?tool=bestpractice.com ​ When EoO is in remission and well controlled, regular clinic visits (i.e., every 3-6 months in children, particularly to monitor growth and nutrition, and every 6-12 months in adults) are required. There are no formal recommendations on routine endoscopic surveillance, and this practice varies depending on the centre.