Evidence
This page contains a snapshot of featured content which highlights evidence addressing key clinical questions including areas of uncertainty. Please see the main topic reference list for details of all sources underpinning this topic.
Cochrane Clinical Answers

Cochrane Clinical Answers (CCAs) provide a readable, digestible, clinically focused entry point to rigorous research from Cochrane systematic reviews. They are designed to be actionable and to inform decision making at the point of care and have been added to relevant sections of the main Best Practice text.
- How does anticoagulation affect outcomes in adults with cerebral venous sinus thrombosis?
- In people with prosthetic heart valves, what are the effects of combined antiplatelet and vitamin K antagonists (VKA) therapy compared with VKA monotherapy?
- How do different warfarin loading doses affect the ability to reach the target international normalized ratio in people newly prescribed anticoagulation?
- How does self-monitoring/management of oral anticoagulation compare with usual care?
- How do anticoagulants compare following total hip or knee replacement or hip fracture repair?
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