Basal cell carcinoma

National Comprehensive Cancer Center risk stratification[44]National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: basal cell skin cancer [internet publication]. https://www.nccn.org/guidelines/category_1

Stratification for local BCC based on risk factors for recurrence. If a patient has any high risk factor, they should be categorised as high risk.

Low risk

• Location and diameter: <2 cm on trunk or extremities

• Clinical boarders: well defined

• Primary versus recurrent: primary

• Immunosuppression: none

• Site of prior radiotherapy: no

• Histological subtype: nodular, superficial, or other non-aggressive growth pattern

• Perineural involvement: none

High risk

• Location and diameter: ≥2 cm on trunk or extremities; or any size on head, neck, hands, feet, pretibial, or anogenital region

• Clinical boarders: poorly defined

• Primary versus recurrent: recurrent

• Immunosuppression: yes

• Site of prior radiotherapy: yes

• Histological subtype: aggressive growth pattern

• Perineural involvement: yes