Upper airway cough syndrome

Prognostic data is limited and variable response rates have been published. Setting appropriate patient expectations is important, as treatment may not completely resolve symptoms.[4]Chung KF, McGarvey L, Song WJ, et al. Cough hypersensitivity and chronic cough. Nat Rev Dis Primers. 2022 Jun 30;8(1):45. https://pmc.ncbi.nlm.nih.gov/articles/PMC9244241 http://www.ncbi.nlm.nih.gov/pubmed/35773287?tool=bestpractice.com ​ Estimates of cough persistence in adults with chronic cough differ between studies.[62]Kang SY, Song WJ, Won HK, et al. Cough persistence in adults with chronic cough: a 4-year retrospective cohort study. Allergol Int. 2020 Oct;69(4):588-93. https://www.sciencedirect.com/science/article/pii/S1323893020300496 http://www.ncbi.nlm.nih.gov/pubmed/32327301?tool=bestpractice.com [63]Koskela HO, Lätti AM, Purokivi MK. Long-term prognosis of chronic cough: a prospective, observational cohort study. BMC Pulm Med. 2017 Nov 21;17(1):146. https://bmcpulmmed.biomedcentral.com/articles/10.1186/s12890-017-0496-1 http://www.ncbi.nlm.nih.gov/pubmed/29162060?tool=bestpractice.com [64]Yousaf N, Montinero W, Birring SS, et al. The long term outcome of patients with unexplained chronic cough. Respir Med. 2013 Mar;107(3):408-12. https://www.resmedjournal.com/article/S0954-6111(12)00429-5/fulltext http://www.ncbi.nlm.nih.gov/pubmed/23261310?tool=bestpractice.com ​​

Chronic cough is commonly due to multiple coexisting causes. If the cough does not completely resolve during treatment, it is important to ensure that possible coexisting causes have been fully investigated.