Case history

Your Organisational Guidance

ebpracticenet urges you to prioritise the following organisational guidance:

MaagklachtenPublished by: NHGLast published: 2025

Case history #1

A 42-year-old man presents with a recent history of abdominal pain, distension, and nausea. Urea breath testing for Helicobacter pylori is positive.

Case history #2

A 58-year-old white woman of North European descent presents with a 2-month history of increasing fatigue, difficulty with ambulation, and memory deficits. Family history is notable for autoimmune disease. Laboratory findings are remarkable for a macrocytic anaemia, a markedly reduced serum vitamin B12, and presence of anti-parietal cell antibodies.

Other presentations

Erosive gastritis may occur in response to non-steroidal anti-inflammatory drugs (NSAIDs), or alcohol use or misuse, and to bile reflux into the stomach following previous gastric surgery or biliary surgery, including cholecystectomy.​[1][2][4][5][6][7] Stress gastritis (most commonly related to mucosal ischaemia) may develop in critically ill patients, generally in the intensive care unit population.[8] Autoimmune gastritis occurs when anti-parietal cell antibodies stimulate a chronic inflammatory, mononuclear, and lymphocytic infiltrate involving the oxyntic mucosa, leading to the loss of parietal and chief cells in the gastric corpus.[2][9] Phlegmonous gastritis is a rare but life-threatening infection of the gastric submucosa and muscularis propria seen in immunocompromised patients.[10][11][12][13]

Use of this content is subject to our disclaimer