Emerging treatments
Povidone-iodine ophthalmic solution
One systematic review and meta-analysis found low certainty evidence to suggest that povidone-iodine ophthalmic solution alone may be more effective than artificial tears in resolving selected ocular signs of epidemic keratoconjunctivitis at 7 days.[104] One randomised phase 3 trial of patients with bacterial conjunctivitis found that combined povidone-iodine ophthalmic solution and dexamethasone ophthalmic suspension did not significantly improve clinical outcomes compared with placebo.[105]
Dexamethasone intracanalicular insert
Dexamethasone intracanalicular insert is approved in the US for the treatment of ocular itching associated with allergic conjunctivitis in children aged ≥2 years and adults. One systematic review and meta-analysis of randomised controlled trials reported a significant and clinically meaningful improvement in conjunctival itching and redness among patients with seasonal/perennial allergic conjunctivitis.[106]
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