Given cardiac tamponade is caused by any disorder that results in pericardial effusion, its epidemiology is directly related to the epidemiology of the causative conditions and risk factors for those disease states. Few direct epidemiological data exist for cardiac tamponade in the literature.[12]Adler Y, Ristić AD, Imazio M, et al. Cardiac tamponade. Nat Rev Dis Primers. 2023 Jul 20;9(1):36.
http://www.ncbi.nlm.nih.gov/pubmed/37474539?tool=bestpractice.com
Cardiac tamponade may occur in up to 13% of patients hospitalised with acute pericarditis and incidence has been shown to be 30% to 44% in patients with large, chronic pericardial effusions (>10 mm on echocardiogram).[13]Vecchié A, Chiabrando JG, Dell MS, et al. Clinical presentation and outcomes of acute pericarditis in a large urban hospital in the United States of America. Chest. 2020 Dec;158(6):2556-67.
https://pmc.ncbi.nlm.nih.gov/articles/PMC7768931
http://www.ncbi.nlm.nih.gov/pubmed/32717264?tool=bestpractice.com
[14]Columbo A, Olson HG, Egan J, et al. Etiology and prognostic implications of a large pericardial effusion in men. Clin Cardiol. 1988 Jun;11(6):389-94.
https://onlinelibrary.wiley.com/doi/abs/10.1002/clc.4960110606
http://www.ncbi.nlm.nih.gov/pubmed/3293859?tool=bestpractice.com
[15]Adler Y, Charron P, Imazio M, et al. 2015 ESC Guidelines for the diagnosis and management of pericardial diseases. Eur Heart J. 2015 Nov 7;36(42):2921-64.
http://eurheartj.oxfordjournals.org/content/36/42/2921.long
http://www.ncbi.nlm.nih.gov/pubmed/26320112?tool=bestpractice.com
It is more common in patients with specific underlying causes such as malignancy (particularly lung and breast cancer), purulent pericarditis, and tuberculosis, but rarer in patients with acute idiopathic pericarditis.[15]Adler Y, Charron P, Imazio M, et al. 2015 ESC Guidelines for the diagnosis and management of pericardial diseases. Eur Heart J. 2015 Nov 7;36(42):2921-64.
http://eurheartj.oxfordjournals.org/content/36/42/2921.long
http://www.ncbi.nlm.nih.gov/pubmed/26320112?tool=bestpractice.com
[16]Sagrista-Sauleda J, Merce J, Permanyer-Miralda G, et al. Clinical clues to the causes of large pericardial effusions. Am J Med. 2000 Aug 1;109(2):95-101.
http://www.ncbi.nlm.nih.gov/pubmed/10967149?tool=bestpractice.com
[17]Selavraju N, Mahadevan G, Liu KY. Cardiac tamponade in a multiracial population: epidemiology, clinical characteristics and survival outcomes - a single centre experience. Eur Heart J. 2023 Feb 1;44(1 suppl):ehac779.077.
https://academic.oup.com/eurheartj/article/44/Supplement_1/ehac779.077/7000507
In people from endemic regions, tuberculosis pericarditis remains a prominent cause of pericardial effusion and tamponade.[18]Gibbs C, Watson RD, Singh SP, et al. Management of pericardial effusion by drainage: a survey of 10 years' experience in a city centre general hospital serving a multiracial population. Postgrad Med J. 2000 Dec;76(902):809-13.
https://academic.oup.com/pmj/article/76/902/809/7040147
http://www.ncbi.nlm.nih.gov/pubmed/11085787?tool=bestpractice.com
[19]Nkoke C, Makoge C, Tewafeu D, et al. Large hemorrhagic pericardial effusion with cardiac tamponade in a 16-year-old adolescent in an endemic area of tuberculosis: a case report. Pan Afr Med J. 2021 Oct 22;40:117.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8627139
http://www.ncbi.nlm.nih.gov/pubmed/34887991?tool=bestpractice.com
Cardiac tamponade can occur at any age but is most commonly seen in middle-aged and older populations, though this depends on the underlying cause.[14]Columbo A, Olson HG, Egan J, et al. Etiology and prognostic implications of a large pericardial effusion in men. Clin Cardiol. 1988 Jun;11(6):389-94.
https://onlinelibrary.wiley.com/doi/abs/10.1002/clc.4960110606
http://www.ncbi.nlm.nih.gov/pubmed/3293859?tool=bestpractice.com
[16]Sagrista-Sauleda J, Merce J, Permanyer-Miralda G, et al. Clinical clues to the causes of large pericardial effusions. Am J Med. 2000 Aug 1;109(2):95-101.
http://www.ncbi.nlm.nih.gov/pubmed/10967149?tool=bestpractice.com