Summary
Definition
History and exam
Key diagnostic factors
- malignancy
- presence of other risk factors
- dyspnoea
- raised jugular venous pressure (JVP)
- distant heart sounds
- pulsus paradoxus
- hypotension
- tachycardia
- recent cardiac surgery or intervention
- Beck's triad: hypotension, distant heart sounds, and raised JVP
Risk factors
- malignancy
- aortic dissection
- purulent pericarditis
- large idiopathic chronic pericardial effusion
- post-cardiac surgery or intervention
- tuberculosis (TB)
- autoimmune disease
- hypothyroidism
- end-stage renal failure
- anticoagulation
Diagnostic investigations
1st investigations to order
- ECG
- transthoracic echocardiogram
- CXR
- FBC
- erythrocyte sedimentation rate/CRP
- cardiac enzymes
Investigations to consider
- cardiac CT
- cardiac MRI
- cardiac catheterisation
- pericardiocentesis fluid for culture and cytology
Treatment algorithm
Contributors
Authors
Antonio Abbate, MD, PhD
Ruth C. Heede Professor of Cardiovascular Medicine
Division of Cardiovascular Medicine
Berne Cardiovascular Research Center
University of Virginia School of Medicine
Charlottesville
VA
Disclosures
AA has received consultant fees from Kiniksa Pharmaceuticals. He is an author of references cited in this topic.
Acknowledgements
Dr Antonio Abbate would like to gratefully acknowledge Dr Vaikom S. Mahadevan, Dr Harsh Agrawal, Dr Jonathan Bella, Dr Liran Blum, and Dr Michael Spinelli, previous contributors to this topic.
Disclosures
VSM declares that he is a proctor for Edwards Lifesciences for transcatheter valves and also a proctor for Abbott for closure devices. HA, JB, LB, and MS declare that they have no competing interests.
Peer reviewers
Ramon Castello, MD
Professor of Medicine
Director of Echocardiography
Mayo Clinic
Jacksonville
FL
Disclosures
RC declares that he has no competing interests.
References
Key articles
Klein AL, Abbara S, Agler DA, et al. American Society of Echocardiography clinical recommendations for multimodality cardiovascular imaging of patients with pericardial disease: endorsed by the Society for Cardiovascular Magnetic Resonance and Society of Cardiovascular Computed Tomography. J Am Soc Echocardiogr. 2013 Sep;26(9):965-1012.Full text Abstract
Adler Y, Charron P, Imazio M, et al. 2015 ESC Guidelines for the diagnosis and management of pericardial diseases. Eur Heart J. 2015 Nov 7;36(42):2921-64.Full text Abstract
Reference articles
A full list of sources referenced in this topic is available here.
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