Case history

Case history #1

A 30-year-old man presents with a swelling on his thigh that has been progressively getting bigger over the last 3 months. He denies trauma but complains of pain sometimes with movement. Routine laboratory tests are all within normal limits. Imaging shows metastases to the lungs.

Case history #2

A 50-year-old man presents with anaemia and a positive faecal immunochemical test. Computed tomography scans show a duodenal mass. Biopsy of mass is positive for CD117 antigen.

Other presentations

Soft-tissue sarcomas consist of numerous subtypes. In general, extremity sarcomas present as masses on the limb, which may or may not be painful. Retroperitoneal/abdominal sarcomas and gastrointestinal stromal tumours present with intra-abdominal symptoms (obstruction, bloating, discomfort, and pain), with or without a palpable mass or evidence of perforation. Chest wall lesions present as a symptomatic or asymptomatic mass. Head and neck sarcomas can present with symptoms related to the mass, including pain and cranial nerve involvement.

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