Occurs in 30% of infected patients.[10]Barlow G, Irving WL, Moss PJ. Infectious disease. In: Feather A, Randall D, Waterhouse M, eds. Kumar & Clark’s clinical medicine. 10th ed. London: Elsevier, 2021. Long-term sequelae may include headache, concentration difficulties, memory impairment, ataxia, tremor, and emotional instability.[13]Lindquist L, Vapalahti O. Tick-borne encephalitis. Lancet. 2008 May 31;371(9627):1861-71.
http://www.ncbi.nlm.nih.gov/pubmed/18514730?tool=bestpractice.com
short term
low
Occurs in 6% of infected patients.[10]Barlow G, Irving WL, Moss PJ. Infectious disease. In: Feather A, Randall D, Waterhouse M, eds. Kumar & Clark’s clinical medicine. 10th ed. London: Elsevier, 2021. Physiotherapy and other long-term supportive treatments may be indicated.[4]Lindquist L. Tick-borne encephalitis. Handb Clin Neurol. 2014 Jul 14;123:531-59.
http://www.ncbi.nlm.nih.gov/pubmed/25015503?tool=bestpractice.com
short term
low
The mortality rate is 1% in patients with Western/European virus infections, and up to 8% in patients with (Ural-) Siberian virus infections.[8]Kuhn JH, Crozier I. Arthropod-borne and rodent-borne virus infections. In: Loscalzo J, Fauci AS, Kasper DL, Hauser SL, Longo DL, Jameson JL, eds. Harrison’s principles of internal medicine. 21st ed. New York: McGraw-Hill, 2022.[15]World Health Organization. Tick-borne encephalitis. 2025 [internet publication].
http://www.who.int/immunization/diseases/tick_encephalitis/en
Early treatment with aciclovir and adequate supportive critical care can decrease mortality associated with TBE.