Hereditary spherocytosis

Screening of the general population is not recommended.

Screening of family members of a known case is recommended (using the following simple tests: haemoglobin, bilirubin, reticulocyte count, and blood smear for spherocytes).[42]MacKinney AA Jr, Morton NE, Kosower NS, et al. Ascertaining genetic carriers of hereditary spherocytosis by statistical analysis of multiple laboratory tests. J Clin Invest. 1962 Mar;41(3):554-67. https://www.jci.org/articles/view/104509 http://www.ncbi.nlm.nih.gov/pubmed/14467968?tool=bestpractice.com