Complications

Complication
Timeframe
Likelihood
long term
low

Sinus tracts may form in osteoarticular sporotrichosis as a result of either progression of the primary infection or as a complication of a prior surgical intervention.[4][5]

variable
medium

Amphotericin B deoxycholate is more likely to cause renal impairment compared with lipid formulations of amphotericin B (i.e., a 50% versus 20% to 30% reduction in glomerular filtration rates may be seen following 4 weeks of amphotericin B deoxycholate or lipid formulation of amphotericin B therapy, respectively). Renal impairment is dose dependent and its incidence increases with increasing amphotericin B treatment duration. It manifests as rising creatinine, azotemia, non-anion gap renal tubular acidosis, hypokalemia, and hypomagnesemia. Aggressive hydration and electrolyte repletion are necessary during amphotericin B therapy.[55]

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