Prognosis
Generally patients with an infection caused by methicillin-sensitive Staphylococcus aureus have better outcomes than those infected with MRSA.[18] Certain genetic factors contribute to poor outcomes, such as the presence of Panton-Valentine leukocidin genes, which are commonly associated with skin and soft-tissue infections, but have also been associated with necrotizing pneumonia and invasive osteomyelitis.[24] However, it is unclear if this gene is merely an epidemiologic marker of community-associated MRSA strains, or a virulence factor. Once infected, a patient is at risk of becoming a carrier, and this should be considered with any future presentation of infection.
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