Prognosis

Spontaneous, complete recovery to normal thyroid function may occur in ≥90% of patients.[2]​ However, the thyroid gland may exhibit irregular scarring between islands of residual functioning parenchyma.

Approximately 15% of patients will have permanent hypothyroidism and require lifelong levothyroxine to normalise the thyroid-stimulating hormone.[2]​[4]​

Specific human leukocyte antigen alleles appear to be associated with increased risk for recurrence.[59]​

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