Epidemiology

The overall age- and sex-adjusted annual incidence rate of subacute thyroiditis is estimated at 4.9 cases per 100,000 per year.[2]

The female-to-male ratio is 3:1, with most cases occurring between the ages of 30 and 50 years.[6]

Seasonal variation has been reported in several studies, whereby increased subacute thyroiditis incidence coincides with peak enterovirus incidence.[1][7][8] ​In one retrospective cohort study of 852 patients, 23% reported respiratory symptoms within one month before the onset of subacute thyroiditis.[1]​

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