Nearly 36 million people annually are estimated to consume amphetamines around the world, and amphetamines are the second most widely misused drug type after cannabis.[10]United Nations Office on Drugs and Crime. World Drug Report 2016. May 2016 [internet publication].
https://www.unodc.org/wdr2016
The use of amphetamines continues to increase in North America, Australia, the Russian Federation, Eastern Europe, China, and Southeast Asia. Many of the countries in which use is growing are emerging economies with large numbers of users younger than 30 years. They constitute new markets for sellers, particularly for MDMA (ecstasy)-related preparations.[10]United Nations Office on Drugs and Crime. World Drug Report 2016. May 2016 [internet publication].
https://www.unodc.org/wdr2016
[11]United Nations Office on Drugs and Crime. 2014 global synthetic drugs assessment: amphetamine-type stimulants and new psychoactive substances. May 2014 [internet publication].
https://www.unodc.org/documents/scientific/2014_Global_Synthetic_Drugs_Assessment_web.pdf
In the United States in 2019, 2.0 million people (aged ≥12 years) had used methamphetamines in the past year, representing 0.7% of the population ages 12 or older.[12]Substance Abuse and Mental Health Services Administration. Key substance use and mental health indicators in the United States: results from the 2019 National Survey on Drug Use and Health. Sep 2020 [internet publication].
https://store.samhsa.gov/product/key-substance-use-and-mental-health-indicators-in-the-united-states-results-from-the-2019-national-survey-on-Drug-Use-and-Health/PEP20-07-01-001?referer=from_search_result
Drug overdose deaths in the US involving a psychostimulant (e.g., methamphetamine, MDMA, dextroamphetamine, levoamphetamine) increased 37% between 2017 and 2018, accounting for 15% of all drug overdose deaths in 2018.[13]Kariisa M, Scholl L, Wilson N, et al. Drug Overdose Deaths Involving Cocaine and Psychostimulants with Abuse Potential - United States, 2003-2017. MMWR Morb Mortal Wkly Rep. 2019 May 3;68(17):388-95.
https://www.doi.org/10.15585/mmwr.mm6817a3
http://www.ncbi.nlm.nih.gov/pubmed/31048676?tool=bestpractice.com