History and exam

Key diagnostic factors

common

older age

Prevalence of heart failure is ≥10% in people ≥70 years of age.[1][11]

positive past medical history

In patients hospitalized for acute heart failure, around 75% have a history of prior heart failure.[11]

Nonadherence to medications is a precipitating factor in patients with acute on chronic heart failure.

Coronary artery disease accounts for around 50% of all patients with acute heart failure.[11][12][13][14]

A history of hypertension is present in 72% of patients in the US and 60% of patients in Europe.[11][13][14]

About 23% of patients in the US and 34% in Europe have valvular disease as an associated condition.[11][14] Both significant stenotic and regurgitant lesions can lead to heart failure.

Atrial fibrillation is present in approximately 35% of cases.[15]​​

Diabetes mellitus is directly related to ischemia and renal failure.

Large pericardial effusions and pericardial constriction can present with symptoms or signs of acute heart failure.

Myocarditis may also cause heart failure.

dyspnea

Dyspnea (including orthopnea or paroxysmal nocturnal dyspnea) is the predominant symptom and is present in the majority of patients with acute heart failure.[9]

pulmonary crepitations

Key finding on chest examination.[9]

peripheral edema

Present in the majority of patients (around 65% of cases).[9][11]

cool peripheries

Due to reduced cardiac output.

uncommon

chest pain

If underlying cardiac ischemia.

third heart sound (S3)

Often difficult to hear, low intensity sound heard early in diastole.

Other diagnostic factors

common

fatigue and weakness or decreased exercise tolerance

Due to poor cardiac functioning.

hypotension

Sign of left and right heart failure.

tachycardia

Due to activation of the sympathetic nervous system or underlying arrhythmia.

elevated jugular venous pressure

Sign of right heart failure.

displaced apex beat (point of maximal impulse)

This, together with elevated jugular venous pressure, third heart sound, crepitations, and edema, suggests a diagnosis of acute heart failure.

dullness to percussion and decreased air entry in lung bases

Suggestive of pleural effusion.

wheezing

Suggests cardiac asthma.

uncommon

palpitations

If underlying arrhythmia.

cough

Due to pulmonary congestion.

syncope

Suggestive of underlying cause, such as significant aortic stenosis or pulmonary embolism.

murmur

Both significant stenotic and regurgitant lesions can lead to heart failure.

ascites

Acute heart failure is a nonhepatic cause of increased portal hypertension, which in turn causes ascites.

hepatomegaly

This may occur due to right-sided heart failure and venous congestion.

central cyanosis

Due to systemic arterial oxygen desaturation.

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