Epidemiology

In the US, the age-adjusted annual incidence rate of mesothelioma was 0.7 per 100,000 population in 2021.[4] The disease is more common in men (male to female ratio of approximately 3:1), particularly non-Hispanic white men.[4] Mesothelioma typically occurs in older adults (sixth to ninth decade of life).[4] In the US, the mesothelioma incidence rate appears to have been declining modestly since 2013.[4]

During the period 1999-2015, 45,221 malignant mesothelioma deaths were reported in the US, 2597 of which occurred in 2015. In England, Scotland, and Wales, there were a combined 2257 deaths attributable to mesothelioma in 2022.[5]​ Global mortality rates vary widely, ranging from 0.5 deaths per million in Brazil and Ecuador to 31 deaths per million in the UK.[6] This variation likely reflects country-to-country disparities in asbestos use and regulation.[6][7]

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