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Last reviewed: 19 Sep 2025
Last updated: 21 Jan 2025

Summary

Definition

History and exam

Key diagnostic factors

  • presence of risk factors
  • history of mechanical trauma
  • past medical history of osteoporosis or neoplasm
  • back pain
  • bruising
  • acute numbness/paraesthesia
  • weakness
  • muscle spasticity/clonus (hypertonicity) or hypotonia
  • hyperreflexia or hyporeflexia
  • Hoffman's sign
  • positive Babinski's sign
  • spinal deformity
  • loss of anal sphincter reflex

Other diagnostic factors

  • absence of bulbocavernosus reflex (S3-S4)
  • signs of spinal shock (hypotonia or flaccidity that resolves within 24 hours)
  • urinary incontinence
  • painless urinary retention

Risk factors

  • falling from a height
  • high-energy mechanism of injury
  • age >65 years
  • concomitant osteoporosis
  • previous vertebral fracture
  • underlying neoplastic lesion
  • underlying metabolic or inflammatory disorders

Diagnostic investigations

1st investigations to order

  • Non-contrast multidetector CT spine (MDCT)

Investigations to consider

  • thoracolumbar spine x-ray (anterior-posterior and lateral views)
  • MRI spine
  • CT myelography
  • MRI with STIR sequence
  • Whole body CT

Treatment algorithm

Contributors

Authors

Besnik Nurboja, BSc, MBBS, MD (Res), MRCS, FRCEM

Consultant in Emergency Medicine

Emergency Medicine

Epsom and St Helier University Hospital NHS Trust

London

UK

Disclosures

BN declares that he has no competing interests.

David Choi, FRCS(SN)
David Choi

Consultant Neurosurgeon and Spinal Surgeon

The National Hospital for Neurology and Neurosurgery

London

UK

Disclosures

DC declares that he has no competing interests.

Peer reviewers

Byron F. Stephens, MD, MSCI

Associate Professor

Vanderbilt University School of Medicine

Nashville

TN

Disclosures

BFS has received Institutional Research Support from Nuvasive and Stryker.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

References

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Key articles

Wendt K, Nau C, Jug M, et al. ESTES recommendation on thoracolumbar spine fractures: January 2023. Eur J Trauma Emerg Surg. 2024 Aug;50(4):1261-75.Full text

American College of Surgeons. Best practices guidelines. Spine injury. Mar 2022 [internet publication].Full text

American College of Radiology. ACR appropriateness criteria: acute spinal trauma. 2024 [internet publication].Full text

National Institute for Health and Care Excellence. Spinal injury: assessment and initial management. Feb 2016 [internet publication].Full text

O'Toole JE, Kaiser MG, Anderson PA, et al. Congress of Neurological Surgeons systematic review and evidence-based guidelines on the evaluation and treatment of patients with thoracolumbar spine trauma: executive summary. Neurosurgery. 2019 Jan 1;84(1):2-6.Full text  Abstract

Reference articles

A full list of sources referenced in this topic is available here.

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