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Last reviewed: 21 Apr 2025
Last updated: 31 Oct 2024

Summary

Definition

History and exam

Key diagnostic factors

  • presence of risk factors
  • snoring, gasping, choking while asleep (obstructive sleep apnoea)
  • night sweats (obstructive sleep apnoea)
  • breathing through an open mouth (obstructive sleep apnoea)
  • sleeping with hyperextended neck (obstructive sleep apnoea)
  • restless sleep and periodic limb movements (obstructive sleep apnoea)
  • secondary nocturnal enuresis (obstructive sleep apnoea)
  • hypertension (obstructive sleep apnoea)
  • inability to fall asleep (sleep association disorder)
  • cataplexy (narcolepsy)
  • hypnagogic or hypnopompic hallucinations (narcolepsy)
  • sleep paralysis (narcolepsy)
  • erratic sleep schedule (delayed sleep-wake phase disorder)

Other diagnostic factors

  • excessive daytime sleepiness
  • difficulty awakening in the morning
  • sleepwalking or talking (obstructive sleep apnoea)
  • sleep attacks (narcolepsy)
  • refusal to sleep in own bedroom (chronic insomnia disorder)

Risk factors

  • craniofacial abnormalities (obstructive sleep apnoea)
  • adenotonsillar hypertrophy (obstructive sleep apnoea)
  • macroglossia (obstructive sleep apnoea)
  • gastro-oesophageal reflux (obstructive sleep apnoea)
  • allergic rhinitis (obstructive sleep apnoea)
  • environmental tobacco smoke exposure (obstructive sleep apnoea)
  • obesity (obstructive sleep apnoea)
  • hypotonia (obstructive sleep apnoea)
  • alcohol (obstructive sleep apnoea)
  • medications (obstructive sleep apnoea)
  • Down's syndrome (obstructive sleep apnoea)
  • evening light exposure (delayed sleep-wake phase disorder)
  • inconsistent parenting style or unrealistic sleep expectations (chronic insomnia disorder)
  • age <6 years (chronic insomnia disorder or obstructive sleep apnoea)
  • adolescent age (delayed sleep-wake phase disorder)
  • distractions in bedroom (delayed sleep-wake phase disorder)
  • traumatic or stressful life events (chronic insomnia disorder)

Diagnostic investigations

1st investigations to order

  • sleep diary
  • polysomnogram (PSG)
  • multiple sleep latency test

Investigations to consider

  • lateral neck films
  • nasal endoscopy
  • overnight oximetry
  • actigraphy
  • audiovisual recording
  • HLA typing

Emerging tests

  • pneumogram
  • cerebrospinal fluid hypocretin levels

Treatment algorithm

Contributors

Authors

Dennis Rosen, MD

Associate Medical Director

Center for Pediatric Sleep Disorders

Boston Children's Hospital

Assistant Professor of Pediatrics

Harvard Medical School

Boston

MA

Disclosures

DR declares that he has no competing interests.

Peer reviewers

Paul Gringras, MB, ChB, MSc, MRCPCH

Consultant in Paediatric Neurodisability

Evelina Children's Hospital

St Thomas' Hospital

London

UK

Disclosures

PG is lead applicant on the ongoing MENDS trial, which is concerned with the use of melatonin in children with neurodevelopmental disorders and impaired sleep.

Leila Kheirandish Gozal, MD

Associate Professor of Pediatrics

Division of Pediatric Pulmonary & Sleep Medicine

University of Chicago

Chicago

IL

Disclosures

LKG is an author of a number of references cited in this topic.

References

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Key articles

American Academy of Sleep Medicine. International Classification of Sleep Disorders – third edition, text revision (ICSD-3-TR). Westchester, IL: American Academy of Sleep Medicine; 2023.

Macias MI, Malhotra S. Behavioral insomnia of childhood. Am J Respir Crit Care Med. 2021 Apr 15;203(8):P20-P21.Full text  Abstract

Ishman SL, Maturo S, Schwartz S, et al. Expert consensus statement: management of pediatric persistent obstructive sleep apnea after adenotonsillectomy. Otolaryngol Head Neck Surg. 2023 Feb;168(2):115-30.Full text  Abstract

Morgenthaler TI, Owens J, Alessi C, et al. Practice parameters for behavioral treatment of bedtime problems and night wakings in infants and young children. Sleep. 2006 Oct;29(10):1277-81.Full text  Abstract

Marcus CL, Moore RH, Rosen CL, et al; Childhood Adenotonsillectomy Trial (CHAT). A randomized trial of adenotonsillectomy for childhood sleep apnea. N Engl J Med. 2013 Jun 20;368(25):2366-76.Full text  Abstract

Reference articles

A full list of sources referenced in this topic is available here.

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