Summary
Definition
History and exam
Other diagnostic factors
- tachypnoea/shortness of breath (SOB)
- faltering growth
- exercise intolerance
- widened pulse pressure
- machine-like continuous murmur/Gibson murmur in children born at full-term
- apnoea
- low diastolic blood pressure (BP)
- irritability
- diaphoresis
- increased respiratory symptoms with upper respiratory tract infection
- murmur heard only during systole
- hyperdynamic precordium
- systolic thrill
- third heart sound heard at apex
- mid-diastolic rumble heard at apex
- bounding peripheral pulses
- pulmonary rales
Risk factors
- prematurity
- maternal rubella
- female sex
- respiratory distress syndrome (RDS)
- high altitude
- family history
- black race
Diagnostic investigations
Treatment algorithm
Contributors
Authors
Kenneth M. Coca, MD
Pediatric Cardiology Fellow
Johns Hopkins All Children’s Hospital
Saint Petersburg
FL
Disclosures
KMC declares that he has no competing interests.
Joyce T. Johnson, MD, MS
Director, Fetal Cardiology
Johns Hopkins All Children’s Hospital
Saint Petersburg
FL
Disclosures
JTJ declares that she has no competing interests.
Acknowledgements
Dr Kenneth M. Coca and Dr Joyce T. Johnson would like to gratefully acknowledge Dr Anji T. Yetman and Dr Nelangi M. Pinto, previous contributors to this topic.
Disclosures
ATY declares that she has no competing interests.
Peer reviewers
Michael Cheung, BSc (Hons), MB ChB, MRCP, FRACP
Acting Head
Department of Cardiology
Royal Children's Hospital
Melbourne
Australia
Disclosures
MC declares that he has no competing interests.
Rajat Bhatt, MD
Assistant Professor
Internal Medicine
Texas Tech University Health Sciences Center (TTUHSC)
Lubbock
TX
Disclosures
RB declares that he has no competing interests.
Henry M. Sondheimer, MD
Professor of Pediatrics
Clinical Director
Pediatric Cardiology
The Children's Hospital
Denver
CO
Disclosures
HMS declares that he has no competing interests.
References
Key articles
Baumgartner H, De Backer J, Babu-Narayan SV, et al. 2020 ESC guidelines for the management of adult congenital heart disease. Eur Heart J. 2021 Feb 11;42(6):563-645.Full text
Hamrick SEG, Sallmon H, Rose AT, et al. Patent ductus arteriosus of the preterm infant. Pediatrics. 2020 Nov;146(5):e20201209.Full text Abstract
Wilson WR, Gewitz M, Lockhart PB, et al. Prevention of viridans group streptococcal infective endocarditis: a scientific statement from the American Heart Association. Circulation. 2021 May 18;143(20):e963-78.Full text Abstract
John AS, Jackson JL, Moons P, et al. Advances in managing transition to adulthood for adolescents with congenital heart disease: a practical approach to transition program design: a scientific statement from the American Heart Association. J Am Heart Assoc. 2022 Apr 5;11(7):e025278.Full text Abstract
Reference articles
A full list of sources referenced in this topic is available here.
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