Summary
Definition
History and exam
Risk factors
- genetic
- infection
- local trauma
- medications
- stress
- smoking
- ethnicity
- alcohol
- greater body mass index (BMI)
Diagnostic investigations
Treatment algorithm
Contributors
Authors
Andrea Chiricozzi, MD
Assistant Professor
University of Pisa
Consultant Dermatologist
University Hospital of Pisa
Pisa
Italy
Disclosures
AC has served as an advisory board member and consultant and has received fees and speaker's honoraria or has participated in clinical trials for AbbVie, Almirall, Biogen, Fresenius Kabi, Leo Pharma, Lilly, Janssen, Novartis, Sanofi Genzyme, and UCB Pharma; AC is also an author of a reference cited in this topic.
Acknowledgements
Dr Andrea Chiricozzi would like to gratefully acknowledge Dr April W. Armstrong and Dr Tsu-Yi Chuang, previous contributors to this topic.
Disclosures
TC declares that he has no competing interests. AWA is an investigator and consultant for Abbott, Amgen, and Janssen; AWA is also an author of references cited in this topic.
Peer reviewers
David Burden, MD, FRCP
Western Infirmary, Glasgow
Consultant Dermatologist Dermatology
Glasgow
UK
Disclosures
DB has been reimbursed as a consultant, researcher, and lecturer for Abbott, Leo, Pfizer, Merck, Janssen-Cilag, and Novartis.
Paradi Mirmirani, MD
Physician
Department of Dermatology
Kaiser Permanente Vallejo Medical Center
Vallejo
CA
Disclosures
PM declares that she has no competing interests.
References
Key articles
National Institute for Health and Care Excellence. Psoriasis: assessment and management. September 2017 [internet publication].Full text
Smith CH, Yiu ZZN, Bale T, et al. British Association of Dermatologists guidelines for biologic therapy for psoriasis 2020: a rapid update. Br J Dermatol. 2020 Oct;183(4):628-37.Full text Abstract
Elmets CA, Lim HW, Stoff B, et al. Joint American Academy of Dermatology – National Psoriasis Foundation guidelines of care for the management and treatment of psoriasis with phototherapy. J Am Acad Dermatol. 2019 Sep;81(3):775-804.Full text Abstract
Menter A, Gelfand JM, Connor C, et al. Joint American Academy of Dermatology - National Psoriasis Foundation guidelines of care for the management of psoriasis with systemic nonbiologic therapies. J Am Acad Dermatol. 2020 Jun;82(6):1445-86.Full text Abstract
Reference articles
A full list of sources referenced in this topic is available here.
Guidelines
- EuroGuiDerm guideline on the systemic treatment of psoriasis vulgaris – part 2: specific clinical and comorbid situations
- Joint AAD-NPF guidelines of care for the management and treatment of psoriasis with topical therapy and alternative medicine modalities for psoriasis severity measures
Calculators
PASI Psoriasis Area and Severity Index Opens in new window
More Calculators
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