History and exam

Key diagnostic factors

common

presence of risk factors

Key risk factors include sexual abuse, pelvic inflammatory disease, endometriosis, and current or previous psychiatric disease.

dysuria

Typically occurs with other irritative voiding symptoms.

dyspareunia

Deep dyspareunia is considered more frequent in endometriosis.[38]

dysmenorrhoea

Indicates uterus or gynaecological organs as 1 source of pain.

abdominal trigger points

Highly localised tenderness, typically at the lateral margin of the rectus sheath or an old scar. Responds well to anaesthetic infiltration.

levator ani tenderness

Often unilateral. The pinpoint location of tenderness must be isolated if anaesthetic infiltration is to be helpful.[39]

cervical motion tenderness

Indicates upper pelvic organs are likely involved: uterus, ovaries. May also occur with bladder pain.

uterine tenderness

Indicates pain of gynaecological origin.

uncommon

abdominal tenderness

If diffuse, suggests a more acute condition overlapping with chronic pain.

vestibular tenderness

May be only a portion of the vestibule. Must be distinguished from hymenal remnant pain.

rectal tenderness

Suggests a component of endometriosis involving the bowel. May indicate an inflammatory bowel disease.

adnexal tenderness

If unilateral, suggests the need for ultrasound characterisation of potential cysts or masses. May be difficult to distinguish following uterine examination.

bladder tenderness

Suggests interstitial cystitis, but is not definitive.

urethral tenderness

Strongly suggests urethritis or urethral diverticulum.

Other diagnostic factors

common

abdominal pain

Generally in the lower abdomen; suggests a trigger point if at the location of an old scar.

nocturia

Typically occurs with other irritative voiding symptoms.

incomplete voiding

Typically occurs with other irritative voiding symptoms.

headache

Commonly associated and suggests multiple pain generators are involved.

uncommon

dyschezia

A symptom of irritable bowel syndrome.

low back pain

Commonly associated and suggests multiple pain generators are involved.

Risk factors

strong

sexual abuse

Substantial evidence supports the relationship between a history of abuse and the development of chronic pelvic pain, and supports the limbic association of chronic pelvic pain.[8][9]​​[19][20]​​​​​​[21]​​

pelvic inflammatory disease

Previous pelvic scarring from surgery or infection often leads to chronic pain.[22]

poor hygiene

Personal hygiene may affect the microflora of the vagina, leading to common infections of the lower reproductive tract. Poor hygiene might result from lack of access to medical services or sanitary products.[21]​​

anxiety or depression

All pain syndromes are worsened in the presence of anxiety or depression.[23]​ The actual causal relationship is less clear.

drug or alcohol use

Patients with chronic pain frequently self-medicate with alcohol. Opioid addiction may precede or result from chronic pain.

pregnancy

Adenomyosis is considered to occur only following pregnancy of some type. It is unclear whether miscarriage or term delivery increases the risk for adenomyosis. Adenomyosis is associated with chronic pelvic pain.[24]

polymenorrhoea

The actual cause of endometriosis is unknown, but it is felt to be associated with having many menstrual periods, during which time endometrial tissue has more of an opportunity to seed the pelvis through retrograde flow. Endometriosis is associated with chronic pelvic pain.

previous caesarean section

Adhesions from surgery, or abdominal wall pain relating to nerve injury, scar tissue formation, or seeding of the surgical wound with endometrial tissue.

endometriosis

Endometriomas provides a pathological basis for chronic pain symptoms. Of women with chronic pelvic pain, 71% to 87% are diagnosed with endometriosis.[25]

weak

adhesions

Adhesive disease provides a pathological basis for chronic pain symptoms.

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