Emerging treatments
Percutaneous pulmonary valve
In the complete surgical repair of TOF, there is dilation or reconstruction of the stenotic portion of the right ventricular outflow tract (RVOT). The repair of the RVOT depends on the anatomy of the pulmonary valve and artery, and infants frequently develop progressive pulmonary regurgitation (as in the case with transannular patch augmentation or progressive pulmonary obstruction) as they grow. It is not uncommon for TOF patients to need pulmonary valve replacement throughout their lives, necessitating multiple by-pass surgeries. Advancements have been made in the development of a transcatheter valved stent, and outcomes of 58 patients undergoing percutaneous pulmonary valve implantation in Europe have recently been reported.[35] In this series, there were three major procedural complications and seven minor complications with no mortality.[35]
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