Summary
Definition
History and exam
Key diagnostic factors
- severe episodic headache
- nausea and vomiting
- light and noise sensitivity
- functional impact
- aura symptoms
- throbbing character
Risk factors
- family history of migraine
- female sex and hormonal changes
- poor sleep quality
- stress
- medication overuse
- periodic syndromes
Diagnostic investigations
Investigations to consider
- brain MRI
- electroencephalogram
- lumbar puncture
- erythrocyte sedimentation rate (ESR) and CRP
- head CT
Treatment algorithm
Contributors
Authors
Cristian Ionita, MD
Associate Professor of Clinical Pediatrics (Neurology)
Yale School of Medicine
New Haven
CT
Disclosures
CI declares that he has no competing interests.
Acknowledgements
Dr Christian Ionita would like to gratefully acknowledge Dr Nick Barnes, a previous contributor to this topic.
Disclosures
NB declares that he has no competing interests.
Peer reviewers
Kenneth Mack, MD, PhD
Medical Director
Mayo Clinic Pediatric Center
Rochester
MN
Disclosures
KM declares that he has no competing interests.
Tony McShane, MBBS
Consultant Paediatric Neurologist
John Radcliffe Hospital
Oxford
UK
Disclosures
TM declares that he has no competing interests.
Sandeep Jayawant, MBBS
Consultant Paediatric Neurologist
John Radcliffe Hospital
Oxford
UK
Disclosures
SJ declares that he has no competing interests.
Howard S. Jacobs, MD
Associate Professor
Co-Director Pediatric Headache Clinic
University of Maryland School of Medicine
Baltimore
MD
Disclosures
HSJ declares that he has no competing interests.
References
Key articles
Headache Classification Committee of the International Headache Society (IHS). The international classification of headache disorders, 3rd edition. Cephalalgia. 2018 Jan;38(1):1-211.Full text Abstract
Oskoui M, Pringsheim T, Billinghurst L, et al. Practice guideline update summary: pharmacologic treatment for pediatric migraine prevention. Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology and the American Headache Society. Neurology. 2019 Sep 10;93(11):500-9.Full text Abstract
Oskoui M, Pringsheim T, Holler-Managan Y, et al. Practice guideline update summary: acute treatment of migraine in children and adolescents. Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology and the American Headache Society. Neurology. 2019 Sep 10;93(11):487-99.Full text Abstract
Richer L, Billinghurst L, Linsdell MA, et al. Drugs for the acute treatment of migraine in children and adolescents. Cochrane Database Syst Rev. 2016 Apr 19;(4):CD005220.Full text Abstract
Reference articles
A full list of sources referenced in this topic is available here.
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