Complications
The risk is high if hypertension develops early in pregnancy.
Increased BPs adversely affect renal function, leading to proteinuria. A urine albumin level of >300 mg in 24 hours with hypertension is diagnostic.
Placental growth factor (PlGF)-based testing, used with standard clinical assessment, can help rule in or rule out pre-eclampsia for women with suspected pre-eclampsia between 20 and 36 weeks plus 6 days of gestation.[29]
Hypertensive disorders of pregnancy are associated with short-term vascular complications, as well as earlier and increased risk of cardiovascular disease.[54][55][56][57] Other risk factors include early adverse changes in lipid and carbohydrate metabolism, and relative hyperandrogenism.[58]
Presence of gestational hypertension increases the risk of macrosomia, intrauterine growth restriction (poor fetal growth), stillbirth, caesarean delivery, and admission of the neonate to the intensive care unit. The co-existence of gestational diabetes further increases the risk.[59]
Mean gestational age and mean birth weight tend to be lower.[60]
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