Results of one study on the natural history of symptomatic lumbar stenosis showed that at 4 years, walking tolerance declined in about 30% of patients, but symptoms improved or remained stable in the remainder.[78]Johnsson KE, Rosen I, Uden A. The natural course of lumbar spinal stenosis. Clin Orthop Relat Res. 1992 Jun;(279):82-6.
http://www.ncbi.nlm.nih.gov/pubmed/1534726?tool=bestpractice.com
Some predictive signs that clinical symptoms may worsen include dural sac cross-sectional area <50 mm2, presence of radicular symptoms and back pain, degenerative spondylolisthesis and/or scoliosis, and symptom duration >1 year.[23]Zileli M, Crostelli M, Grimaldi M, et al. Natural course and diagnosis of lumbar spinal stenosis: WFNS spine committee recommendations. World Neurosurg X. 2020 Jul;7:100073.
https://www.doi.org/10.1016/j.wnsx.2020.100073
http://www.ncbi.nlm.nih.gov/pubmed/32613187?tool=bestpractice.com
Prognosis in patients initially treated with medical or physiotherapy is variable. Studies show that among treated patients without surgery, about 50% remain unchanged, 25% improve, and 25% worsen (mean follow-up was 49 months, range 10 to 103 months).[78]Johnsson KE, Rosen I, Uden A. The natural course of lumbar spinal stenosis. Clin Orthop Relat Res. 1992 Jun;(279):82-6.
http://www.ncbi.nlm.nih.gov/pubmed/1534726?tool=bestpractice.com
Several prospective studies have shown significantly improved long-term (4 to 6 years) outcomes in patients treated surgically rather than non-surgically.[79]Tenhula J, Lenke LG, Bridwell KH, et al. Prospective functional evaluation of the surgical treatment of neurogenic claudication in patients with lumbar spinal stenosis. J Spinal Disord. 2000 Aug;13(4):276-82.
http://www.ncbi.nlm.nih.gov/pubmed/10941885?tool=bestpractice.com
[80]Amundsen T, Weber H, Nordal HJ, et al. Lumbar spinal stenosis: conservative or surgical management?: a prospective 10-year study. Spine (Phila Pa 1976). 2000 Jun 1;25(11):1424-35.
http://www.ncbi.nlm.nih.gov/pubmed/10828926?tool=bestpractice.com
In the Maine Lumbar Spine Study, patients undergoing surgery as their initial treatment had better leg pain relief and greater back-related functional status after 8 to 10 years of follow-up. However, favourable long-term outcomes were only reported by about one half of the patients, regardless of the initial treatment given.[81]Atlas SJ, Keller RB, Wu YA, et al. Long-term outcomes of surgical and nonsurgical management of lumbar spinal stenosis: 8 to 10 year results from the Maine lumbar spine study. Spine (Phila Pa 1976). 2005 Apr 15;30(8):936-43.
http://www.ncbi.nlm.nih.gov/pubmed/15834339?tool=bestpractice.com
Short-term and intermediate surgical outcomes are generally very good to excellent. A success rate of 78% to 88% was found at 6 weeks and 6 months; this rate dropped to 70% at 1 year and 5 years.[82]Javid MJ, Hadar EJ. Long-term follow-up review of patients who underwent laminectomy for lumbar stenosis: a prospective study. J Neurosurg. 1998 Jul;89(1):1-7.
http://www.ncbi.nlm.nih.gov/pubmed/9647165?tool=bestpractice.com
Analysis of a 5-year follow-up of post-laminectomy patients showed excellent results at 2 years (67%), but this fell to only 52% at 5 years, and 18% of patients underwent another operation.[83]Jonsson B, Annertz M, Sjoberg C, et al. A prospective and consecutive study of surgically treated lumbar spinal stenosis. part II: five-year follow-up by an independent observer. Spine (Phila Pa 1976). 1997 Dec 15;22(24):2938-44.
http://www.ncbi.nlm.nih.gov/pubmed/9431630?tool=bestpractice.com
Studies show that surgery can be performed safely with satisfactory results in many patients aged 70-89 years who can otherwise tolerate the procedure.[84]Vitaz TW, Raque GH, Shields CB, et al. Surgical treatment of lumbar spinal stenosis in patients older than 75 years of age. J Neurosurg. 1999 Oct;91(2 Suppl):181-5.
http://www.ncbi.nlm.nih.gov/pubmed/10505502?tool=bestpractice.com
[85]Kalbarczyk A, Lukes A, Seiler RW. Surgical treatment of lumbar spinal stenosis in the elderly. Acta Neurochir (Wien). 1998;140(7):637-41.
http://www.ncbi.nlm.nih.gov/pubmed/9781274?tool=bestpractice.com
Recurrence of back pain can occur after surgery. Patients may initially have improvement in symptoms and subsequently deteriorate over time. One study found 27% recurrence of symptoms after 5 years of follow-up.[86]Caputy AJ, Luessenhop AJ. Long-term evaluation for decompressive surgery for degenerative lumbar stenosis. J Neurosurg. 1992 Nov;77(5):669-76.
http://www.ncbi.nlm.nih.gov/pubmed/1403105?tool=bestpractice.com
Re-stenosis at the operated level, stenosis at a new level, development of herniated lumbar disc and late instability are among the reasons for failed surgery.[86]Caputy AJ, Luessenhop AJ. Long-term evaluation for decompressive surgery for degenerative lumbar stenosis. J Neurosurg. 1992 Nov;77(5):669-76.
http://www.ncbi.nlm.nih.gov/pubmed/1403105?tool=bestpractice.com
Generally, 75% of these surgical failures respond to further surgery. Results from the Spine Patient Outcomes Research Trial (SPORT) trial demonstrated that patients treated non-operatively improved minimally while those treated surgically improved significantly more, at up to 4 years of follow-up.[59]Weinstein JN, Lurie JD, Tosteson TD, et al. Surgical compared with nonoperative treatment for lumbar degenerative spondylolisthesis: four-year results in the Spine Patient Outcomes Research Trial (SPORT) randomized and observational cohorts. J Bone Joint Surg Am. 2009 Jun;91(6):1295-304.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686131
http://www.ncbi.nlm.nih.gov/pubmed/19487505?tool=bestpractice.com
This was apparent in all primary and secondary outcomes including SF-36 bodily pain, physical function, and in the Oswestry Disability Index. Similar findings were observed for patients with degenerative spondylolisthesis.[59]Weinstein JN, Lurie JD, Tosteson TD, et al. Surgical compared with nonoperative treatment for lumbar degenerative spondylolisthesis: four-year results in the Spine Patient Outcomes Research Trial (SPORT) randomized and observational cohorts. J Bone Joint Surg Am. 2009 Jun;91(6):1295-304.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686131
http://www.ncbi.nlm.nih.gov/pubmed/19487505?tool=bestpractice.com