Long-term prognosis is unclear. Epidemiological studies have suggested that symptoms tend to improve with increasing age, with less frequent cluster periods and more prolonged remissions between cluster periods.[5]Wei DY, Yuan Ong JJ, Goadsby PJ. Cluster headache: epidemiology, pathophysiology, clinical features, and diagnosis. Ann Indian Acad Neurol. 2018 Apr;21(suppl 1):S3-S8.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909131
http://www.ncbi.nlm.nih.gov/pubmed/29720812?tool=bestpractice.com
[9]May A. Cluster headache: pathogenesis, diagnosis, and management. Lancet. 2005 Sep 3-9;366(9488):843-55.
http://www.ncbi.nlm.nih.gov/pubmed/16139660?tool=bestpractice.com