This is one of the most common movement disorders worldwide. Prevalence and incidence increase with age; more than 50% of patients are aged >70 years.[6]Louis ED. Clinical practice. Essential tremor. N Engl J Med. 2001 Sep 20;345(12):887-91.
http://www.ncbi.nlm.nih.gov/pubmed/11565522?tool=bestpractice.com
[13]Louis ED. Essential tremor. Lancet Neurol. 2005 Feb;4(2):100-10.
http://www.ncbi.nlm.nih.gov/pubmed/15664542?tool=bestpractice.com
However, the condition can appear in early adulthood in those who have a family history of essential tremor (ET).[14]Shanker V. Essential tremor: diagnosis and management. BMJ. 2019 Aug 5;366:l4485.
https://www.bmj.com/content/366/bmj.l4485.long
http://www.ncbi.nlm.nih.gov/pubmed/31383632?tool=bestpractice.com
One meta-analysis of 42 population-based prevalence studies in 23 countries revealed an overall prevalence of 1.33% (95% CI 0.88% to 2.02%) across all ages and a prevalence of 5.79% in those aged 65 years or older.[15]Louis ED, McCreary M. How common is essential tremor? Update on the worldwide prevalence of essential tremor. Tremor Other Hyperkinet Mov (N Y). 2021;11:28.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8269764
http://www.ncbi.nlm.nih.gov/pubmed/34277141?tool=bestpractice.com
US prevalence estimates range from 0.3% (all ages) to 3.9% (>65 years of age), and seem to be greater in Americans with white ancestry than in those with black ancestry.[16]Haerer AF, Anderson DW, Schoenberg BS. Prevalence of essential tremor. Results from the Copiah County study. Arch Neurol. 1982 Dec;39(12):750-1.
http://www.ncbi.nlm.nih.gov/pubmed/7138316?tool=bestpractice.com
[17]Louis ED, Fried LP, Fitzpatrick AL, et al. Regional and racial differences in the prevalence of physician-diagnosed essential tremor in the United States. Mov Disord. 2003 Sep;18(9):1035-40.
http://www.ncbi.nlm.nih.gov/pubmed/14502671?tool=bestpractice.com
[18]Louis ED, Marder K, Cote L, et al. Differences in the prevalence of essential tremor among elderly African Americans, whites, and Hispanics in northern Manhattan, NY. Arch Neurol. 1995 Dec;52(12):1201-5.
http://www.ncbi.nlm.nih.gov/pubmed/7492295?tool=bestpractice.com
[19]Rajput AH, Offord KP, Beard CM, et al. Essential tremor in Rochester, Minnesota: a 45-year study. J Neurol Neurosurg Psychiatry. 1984 May;47(5):466-70.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1027820/pdf/jnnpsyc00121-0036.pdf
http://www.ncbi.nlm.nih.gov/pubmed/6736976?tool=bestpractice.com
A 45-year study of ET in Rochester, Minnesota reported an annual incidence of 24 per 100,000 population across all age groups.[19]Rajput AH, Offord KP, Beard CM, et al. Essential tremor in Rochester, Minnesota: a 45-year study. J Neurol Neurosurg Psychiatry. 1984 May;47(5):466-70.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1027820/pdf/jnnpsyc00121-0036.pdf
http://www.ncbi.nlm.nih.gov/pubmed/6736976?tool=bestpractice.com
More than 50% of cases are patients >70 years of age.[6]Louis ED. Clinical practice. Essential tremor. N Engl J Med. 2001 Sep 20;345(12):887-91.
http://www.ncbi.nlm.nih.gov/pubmed/11565522?tool=bestpractice.com