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Malignant hyperthermia

The mechanical response of normal and MH-susceptible muscle (positive) to direct stimulation in the presence of 3% halothane

From the collection of Dr Sheila Muldoon

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Malignant hyperthermia

Diagnostic pathway for investigation of MH susceptibility. IVCT, in vitro contracture test; MH, malignant hyperthermia; MHN (MH negative or normal), classification applied when all contracture tests are negative; MHShc, MHSh, and MHSc, classifications are applied when contracture responses to both halothane and caffeine are abnormal, response to halothane alone is abnormal, or response to caffeine alone is abnormal, respectively. *Patients who should be asked to take part in research studies of the genetic basis of malignant hyperthermia

Hopkins PM et al. Br J Anaesth. 2015 Oct;115(4):531-9. Used with permission

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Malignant hyperthermia

The mechanical response of normal and MH-susceptible muscle (positive) to direct stimulation in the presence of incremental administration of caffeine

From the collection of Dr Sheila Muldoon

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