Evidence

This page contains a snapshot of featured content which highlights evidence addressing key clinical questions including areas of uncertainty. Please see the main topic reference list for details of all sources underpinning this topic.

Cochrane Clinical Answers

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Cochrane Clinical Answers (CCAs) provide a readable, digestible, clinically focused entry point to rigorous research from Cochrane systematic reviews. They are designed to be actionable and to inform decision making at the point of care and have been added to relevant sections of the main Best Practice text.

  • What is the accuracy of procalcitonin (PCT), C‐reactive protein (CRP), and erythrocyte sedimentation rate (ESR) for the diagnosis of acute pyelonephritis in children?
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  • How does antibiotic treatment compare with no treatment or placebo for preventing recurrent urinary tract infection (UTI) in children?
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  • What are the effects of antibiotics with/without surgical implantation of ureters or endoscopic injection for children with primary vesicoureteric reflux?
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