Varicose veins

Non-thermal non-tumescent endovenous ablation

Options for non-thermal non-tumescent endovenous ablation include using mechanochemical ablation (MOCA) or cyanoacrylate glue (CAG) occlusion.[46]Bootun R, Lane TR, Davies AH. The advent of non-thermal, non-tumescent techniques for treatment of varicose veins. Phlebology. 2016 Feb;31(1):5-14. http://www.ncbi.nlm.nih.gov/pubmed/26130051?tool=bestpractice.com [47]Vähäaho S, Mahmoud O, Halmesmäki K, et al. Randomized clinical trial of mechanochemical and endovenous thermal ablation of great saphenous varicose veins. Br J Surg. 2019 Apr;106(5):548-54. http://www.ncbi.nlm.nih.gov/pubmed/30908611?tool=bestpractice.com [48]Gibson K, Morrison N, Kolluri R, et al. Twenty-four month results from a randomized trial of cyanoacrylate closure versus radiofrequency ablation for the treatment of incompetent great saphenous veins. J Vasc Surg Venous Lymphat Disord. 2018 Sep;6(5):606-13. https://www.doi.org/10.1016/j.jvsv.2018.04.009 http://www.ncbi.nlm.nih.gov/pubmed/29914814?tool=bestpractice.com Early evidence suggests equivalent quality of life outcomes with a reduced pain profile compared with endothermal ablation with no difference between MOCA and CAG yet found on head to head comparison.[49]Lane T, Bootun R, Dharmarajah B, et al. A multi-centre randomised controlled trial comparing radiofrequency and mechanical occlusion chemically assisted ablation of varicose veins - final results of the Venefit versus Clarivein for varicose veins trial. Phlebology. 2017 Mar;32(2):89-98. http://www.ncbi.nlm.nih.gov/pubmed/27221810?tool=bestpractice.com