Criteria

Eron classification, 2003[2][80]​​

Classifies skin and soft-tissue infections based on the severity of local and systemic signs, and any comorbidity, to help guide clinical management.

Class I: no signs of systemic toxicity and no uncontrolled comorbidities.

Class II: systemically ill or systemically well, but with a comorbidity (e.g., peripheral vascular disease, chronic venous insufficiency, or obesity) that may complicate or delay resolution of infection.

Class III: significant systemic signs, such as acute confusion, tachycardia, tachypnea, or hypotension; unstable comorbidities that may interfere with a response to treatment; or a limb-threatening infection due to vascular compromise.

Class IV: sepsis or a severe life-threatening infection, such as necrotizing fasciitis.

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