Amebic colitis
Mortality rate is less than 2% in uncomplicated disease.
Severe disease manifestations of toxic megacolon, colonic perforation with resultant peritonitis or bowel necrosis, typically carry over 50% mortality.[1]Haque R, Huston CD, Hughes M, et al. Amebiasis. New Engl J Med. 2003;348:1565-73.
http://www.ncbi.nlm.nih.gov/pubmed/12700377?tool=bestpractice.com
[2]Petri WA Jr, Singh U. Diagnosis and management of amebiasis. Clin Infect Dis. 1999;29:1117-25.
http://www.ncbi.nlm.nih.gov/pubmed/10524950?tool=bestpractice.com
[5]Stanley SL Jr. Amoebiasis. Lancet. 2003;361:1025-34.
http://www.ncbi.nlm.nih.gov/pubmed/12660071?tool=bestpractice.com
[7]Shirley DT, Farr L, Watanabe K, et al. A review of the global burden, new diagnostics, and current therapeutics for amebiasis. Open Forum Infect Dis. 2018 Jul;5(7):ofy161.
https://academic.oup.com/ofid/article/5/7/ofy161/5049601
http://www.ncbi.nlm.nih.gov/pubmed/30046644?tool=bestpractice.com
Liver abscess
Mortality rate is less than 2%.
Complications include extension of the abscess into peritoneum, pleural cavity, or pericardium, and hematogenous dissemination to the brain, lung, and skin.[1]Haque R, Huston CD, Hughes M, et al. Amebiasis. New Engl J Med. 2003;348:1565-73.
http://www.ncbi.nlm.nih.gov/pubmed/12700377?tool=bestpractice.com
[2]Petri WA Jr, Singh U. Diagnosis and management of amebiasis. Clin Infect Dis. 1999;29:1117-25.
http://www.ncbi.nlm.nih.gov/pubmed/10524950?tool=bestpractice.com
[3]Solaymani-Mohammadi S, Lam M, Zunt JR. Entamoeba histolytica encephalitis diagnosed by polymerase chain reaction of cerebrospinal fluid. Trans R Soc Trop Med Hyg. 2007;101:311-13.
http://www.ncbi.nlm.nih.gov/pubmed/16930651?tool=bestpractice.com
[5]Stanley SL Jr. Amoebiasis. Lancet. 2003;361:1025-34.
http://www.ncbi.nlm.nih.gov/pubmed/12660071?tool=bestpractice.com