Body mass index (BMI) should be calculated and plotted at each visit to monitor for effects of treatment. Blood pressure should be monitored routinely.[3]Hampl SE, Hassink SG, Skinner AC, et al. Clinical practice guideline for the evaluation and treatment of children and adolescents with obesity. Pediatrics. 2023 Feb 1;151(2):e2022060640.
https://publications.aap.org/pediatrics/article/151/2/e2022060640/190443/Clinical-Practice-Guideline-for-the-Evaluation-and?autologincheck=redirected
http://www.ncbi.nlm.nih.gov/pubmed/36622115?tool=bestpractice.com
Monitoring of psychosocial function and using an evaluation tool when a patient presents with symptoms of depression is also advised.[3]Hampl SE, Hassink SG, Skinner AC, et al. Clinical practice guideline for the evaluation and treatment of children and adolescents with obesity. Pediatrics. 2023 Feb 1;151(2):e2022060640.
https://publications.aap.org/pediatrics/article/151/2/e2022060640/190443/Clinical-Practice-Guideline-for-the-Evaluation-and?autologincheck=redirected
http://www.ncbi.nlm.nih.gov/pubmed/36622115?tool=bestpractice.com
As per the American Diabetes Association recommendations, risk-based screening for prediabetes and/or type 2 diabetes mellitus should be considered after the onset of puberty or after 10 years of age, whichever occurs earlier, in children and adolescents with a BMI ≥85th percentile who have one or more risk factors for diabetes mellitus. Risk factors include maternal history of diabetes mellitus or maternal gestational diabetes during the child’s gestation; family history of type 2 diabetes mellitus in first- or second-degree relative; Native American, African American, Latino, Asian American, Pacific Islander race/ethnicity; signs of insulin resistance or conditions associated with insulin resistance (acanthosis nigricans, hypertension, dyslipidemia, polycystic ovary syndrome, or small-for-gestational-age birth weight). Screening should include fasting blood glucose, a 2-h plasma glucose during a 75-g oral glucose tolerance test, or hemoglobin A1c level checked at a minimum of every 2 years or more frequently if BMI is increasing or risk factor profile is deteriorating. Reports of type 2 diabetes mellitus before age 10 years exist, and screening can be considered with numerous risk factors.[3]Hampl SE, Hassink SG, Skinner AC, et al. Clinical practice guideline for the evaluation and treatment of children and adolescents with obesity. Pediatrics. 2023 Feb 1;151(2):e2022060640.
https://publications.aap.org/pediatrics/article/151/2/e2022060640/190443/Clinical-Practice-Guideline-for-the-Evaluation-and?autologincheck=redirected
http://www.ncbi.nlm.nih.gov/pubmed/36622115?tool=bestpractice.com
[77]American Diabetes Association. Standards of care in diabetes - 2024. Diabetes Care. 2024 Jan 1;47(suppl 1):S1-321.
https://diabetesjournals.org/care/issue/47/Supplement_1
[78]American Diabetes Association Professional Practice Committee. 14. Children and adolescents: standards of care in diabetes-2025. Diabetes Care. 2025 Jan 1;48(supplement_1):S283-S305.
https://diabetesjournals.org/care/article/48/Supplement_1/S283/157559/14-Children-and-Adolescents-Standards-of-Care-in
http://www.ncbi.nlm.nih.gov/pubmed/39651980?tool=bestpractice.com
In addition, when considering type 2 diabetes mellitus screening, panel of pancreatic autoantibodies should be tested to exclude the possibility of autoimmune type 1 diabetes mellitus.[78]American Diabetes Association Professional Practice Committee. 14. Children and adolescents: standards of care in diabetes-2025. Diabetes Care. 2025 Jan 1;48(supplement_1):S283-S305.
https://diabetesjournals.org/care/article/48/Supplement_1/S283/157559/14-Children-and-Adolescents-Standards-of-Care-in
http://www.ncbi.nlm.nih.gov/pubmed/39651980?tool=bestpractice.com
Fasting lipoproteins and liver function tests should also be checked routinely. The American Academy of Pediatrics expert committee suggests screening for lipid abnormalities, abnormal glucose metabolism, and abnormal liver function every 2 years starting at 10 years of age for children with BMI of 95th percentile and those with BMI of 85th to 94th percentile who have other risk factors.[3]Hampl SE, Hassink SG, Skinner AC, et al. Clinical practice guideline for the evaluation and treatment of children and adolescents with obesity. Pediatrics. 2023 Feb 1;151(2):e2022060640.
https://publications.aap.org/pediatrics/article/151/2/e2022060640/190443/Clinical-Practice-Guideline-for-the-Evaluation-and?autologincheck=redirected
http://www.ncbi.nlm.nih.gov/pubmed/36622115?tool=bestpractice.com
In children ages 10 or over who are overweight (BMI 85th to 94th percentile) consider screening for lipid abnormalities.[3]Hampl SE, Hassink SG, Skinner AC, et al. Clinical practice guideline for the evaluation and treatment of children and adolescents with obesity. Pediatrics. 2023 Feb 1;151(2):e2022060640.
https://publications.aap.org/pediatrics/article/151/2/e2022060640/190443/Clinical-Practice-Guideline-for-the-Evaluation-and?autologincheck=redirected
http://www.ncbi.nlm.nih.gov/pubmed/36622115?tool=bestpractice.com