Monitoring

Follow-up recommendations vary depending on the size of oesophageal varices, and whether the patient has previously had oesophageal variceal bleeding.[5][6][29]​​​

Compensated cirrhosis without varices on screening endoscopy:

  • The National Institute for Health and Care Excellence (NICE) in the UK recommends surveillance using upper gastrointestinal endoscopy every 3 years for patients with no varices detected on endoscopy.[17]

  • The British Society of Gastroenterology (BSG) recommends endoscopy at 2- to 3-year intervals for these patients.[5]

Cirrhosis with small varices on screening endoscopy:

  • The BSG recommends annual endoscopy.[5] If there is clear evidence of disease progression, the BSG recommends modifying the endoscopy intervals according to clinical need.[5] 

Following variceal eradication by banding ligation:

  • Endoscopy should be performed at 3 months after varices have been eliminated, and then every 6 months.[5]

Following successful transjugular intrahepatic portosystemic shunt (TIPS) during the acute bleeding episode:

  • A Doppler ultrasound is recommended a week after TIPS implantation in patients with prothrombotic conditions (e.g., Budd-Chiari syndrome), and in other patients if TIPS dysfunction is suspected.[55]

  • Most patients undergoing TIPS have cirrhosis; in these patients, Doppler ultrasound surveillance can be incorporated into routine 6-monthly hepatocellular carcinoma screening, where this is offered.[55]

  • Routine transjugular venography is not recommended. It should be reserved for cases where stent dysfunction is detected on Doppler ultrasound or is clinically suspected (e.g., recurrent ascites).[55]

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