There are several methods to prevent urinary tract infections in women, which may help prevent ascending urinary tract infections. General methods to advise include:[26]Public Health England; NHS England. Treating your infection: urinary tract infection (UTI). October 2020 [internet publication].
https://www.rcgp.org.uk/clinical-and-research/resources/toolkits/amr/target-antibiotics-toolkit/-/media/85AAD1D4DDEF455A85E0416C3BB714AE.ashx
Drink enough fluid during the day to maintain bladder hygiene, and know when to increase intake, such as during hot weather
Improve voiding habits by always responding to initial urge to void
Void after intercourse to rid urethra of bacteria acquired during sex, and if there is a history of atypical anatomy or recurrent urinary tract infections
Wipe from front to back after using the toilet in order to avoid spreading bacteria from bowel to bladder.
Reducing the risk of recurrent urinary tract infections (UTIs) will aid the prevention of recurring pyelonephritis. Agents such as cranberry products, D-mannose, and topical oestrogen preparations are being investigated with potential to reduce the recurrence of UTIs, but there is currently insufficient evidence for guidelines to recommend them.[3]Scottish Intercollegiate Guidelines Network. Management of suspected bacterial lower urinary tract infection in adult women. September 2020 [internet publication].
https://www.sign.ac.uk/media/1766/sign-160-uti-0-1_web-version.pdf
With regard to topical oestrogen preparations, this would be an unlicensed use and there are known side effects.[3]Scottish Intercollegiate Guidelines Network. Management of suspected bacterial lower urinary tract infection in adult women. September 2020 [internet publication].
https://www.sign.ac.uk/media/1766/sign-160-uti-0-1_web-version.pdf
Antibiotics may be necessary in some patients for treatment of recurrent UTI, but the long-term risks and benefits should be considered alongside appropriate antimicrobial stewardship. Use with caution in women aged over 65 years.[3]Scottish Intercollegiate Guidelines Network. Management of suspected bacterial lower urinary tract infection in adult women. September 2020 [internet publication].
https://www.sign.ac.uk/media/1766/sign-160-uti-0-1_web-version.pdf