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Last reviewed: 19 Sep 2025
Last updated: 11 Jul 2024

Summary

Definition

History and exam

Key diagnostic factors

  • chest pain
  • dyspnoea
  • ipsilateral reduced breath sounds
  • ipsilateral hyperinflation of the hemithorax with hyper-resonance on percussion
  • hypoxia
  • presence of risk factors
  • cardiopulmonary deterioration
  • trachea shifted to the contralateral side
  • sweating

Risk factors

  • cigarette smoking
  • family history of pneumothorax
  • tall and slender body build
  • age <40 years
  • recent invasive medical procedure
  • chest trauma
  • acute severe asthma
  • COPD
  • tuberculosis
  • AIDS-related Pneumocystis jirovecii infection
  • cystic fibrosis
  • lymphangioleiomyomatosis
  • Marfan syndrome
  • homocystinuria
  • primary lung cancer and metastatic cancer to the lungs
  • Birt-Hogg-Dube syndrome
  • pulmonary Langerhans cell histiocytosis
  • Erdheim-Chester disease

Diagnostic investigations

Investigations to consider

  • chest ultrasound
  • CT chest
  • arterial blood gas (ABG)

Treatment algorithm

Contributors

Expert advisers

Amy Binnion, BSc (Biochemistry), MB BS, MRCP, PhD

Consultant Respiratory Physician

Respiratory Medicine Institution

Nottingham University Hospitals NHS Trust

Nottingham

UK

Disclosures

.AB has attended a conference fully funded for all delegates by industry sponsorship from multiple sponsors.

Acknowledgements

BMJ Best Practice would like to gratefully acknowledge the previous team of expert contributors, whose work has been retained in parts of the content:

Jonathan Bennett MD

Honorary Professor of Respiratory Sciences

University of Leicester

Respiratory Consultant

Glenfield Hospital

Leicester

UK

Claire Vella MD, MRCP

Clinical Fellow Lung Cancer and Interventional Pulmonology

Glenfield Hospital

Leicester

UK

Onyeka Umerah

Respiratory Registrar

Glenfield Hospital

University Hospitals of Leicester NHS Trust

Leicester

UK

Lonny Yarmus, DO, MBA

Associate Professor of Medicine and Oncology

Clinical Director, Division of Pulmonary and Critical Care

Director, Interventional Pulmonology Research Core

Johns Hopkins Medical Institutions

Baltimore

MD

Jason Akulian, MD, MPH

Assistant Professor of Medicine

Director, Interventional Pulmonology

Carolina Center for Pleural Disease

University of North Carolina

Chapel Hill

NC

Disclosures

JB is deputy medical director of RCP Invited Service Reviews. CV declares that she has no competing interests. OU declares that she has no competing interests. LY has received research grants and consulting fees from Olympus, Inc, the manufacturer of the Spiration intrabronchial valve. JA declares that he has no competing interests.

Peer reviewers

Matthew Knight, PGCertEd MD FRCP FRCP(Edin)

Associate Postgraduate Dean

Health Education England

Royal College of Physicians College Tutor

Consultant Respiratory Physician

Watford General Hospital

West Hertfordshire Hospitals NHS Trust

Disclosures

MK was collaborator and site principal investigator for the randomised ambulatory management of primary pneumothorax (RAMPP) trial, which received funding from Rocket Medical. MK has attended meetings sponsored by Rocket Medical.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

References

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Key articles

Tschopp JM, Bintcliffe O, Astoul P, et al. ERS task force statement: diagnosis and treatment of primary spontaneous pneumothorax. Eur Respir J. 2015 Aug;46(2):321-35.Full text  Abstract

Roberts ME, Rahman NM, Maskell NA, et al; BTS Pleural Guideline Development Group. British Thoracic Society guideline for pleural disease. Thorax. 2023 Jul;78(suppl 3):s1-s42.Full text  Abstract

Asciak R, Bedawi EO, Bhatnagar R, et al. British Thoracic Society clinical statement on pleural procedures. Thorax. 2023 Jul;78(suppl 3):s43-68.Full text  Abstract

Reference articles

A full list of sources referenced in this topic is available here.

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