Pancreatic cancer is a disease with a poor prognosis. It is estimated to account for 67,440 new cases (3.3% of all new cancer diagnoses) in the US in 2025.[8]National Institutes of Health; National Cancer Institute. Cancer stat facts: pancreatic cancer. 2025 [internet publication].
https://seer.cancer.gov/statfacts/html/pancreas.html
Pancreatic cancer is the third most common cause of death in the US; it is estimated that 51,980 people will die from pancreatic cancer in the US in 2025.[8]National Institutes of Health; National Cancer Institute. Cancer stat facts: pancreatic cancer. 2025 [internet publication].
https://seer.cancer.gov/statfacts/html/pancreas.html
Between 2018 and 2022, the median age at diagnosis of pancreatic cancer in the US was 71 years, and between 2019 and 2023, the median age at death in the US was 73 years.[8]National Institutes of Health; National Cancer Institute. Cancer stat facts: pancreatic cancer. 2025 [internet publication].
https://seer.cancer.gov/statfacts/html/pancreas.html
The lifetime risk of developing pancreatic cancer is approximately 1.6%. According to the US data from 2015 to 2021, the 5-year survival rate is 13.3%.[8]National Institutes of Health; National Cancer Institute. Cancer stat facts: pancreatic cancer. 2025 [internet publication].
https://seer.cancer.gov/statfacts/html/pancreas.html
In one European systematic review, the age-standardised incidence of pancreatic cancer was 7.6 in 100,000 people per year in men and 4.9 in 100,000 people per year in women. Overall median survival from diagnosis was 4.6 months.[9]Carrato A, Falcone A, Ducreux M, et al. A systematic review of the burden of pancreatic cancer in Europe: real-world impact on survival, quality of life and costs. J Gastrointest Cancer. 2015 Sep;46(3):201-11.
https://www.doi.org/10.1007/s12029-015-9724-1
http://www.ncbi.nlm.nih.gov/pubmed/25972062?tool=bestpractice.com
Around 46,500 men and 46,000 women in Europe and around 5400 men and 5100 women in the UK are estimated to die from pancreatic cancer in 2025.[10]Santucci C, Mignozzi S, Levi F, et al. European cancer mortality predictions for the year 2025 with focus on breast cancer. Ann Oncol. 2025 Apr;36(4):460-8.
https://www.annalsofoncology.org/article/S0923-7534(25)00022-5/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/40074664?tool=bestpractice.com