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 * Pikaday
 * Copyright © 2014 David Bushell | BSD & MIT license | https://dbushell.com/
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-0.8125rem;position:relative;top:-0.9375rem;line-height:1.2;width:1.875rem;height:1.875rem;display:flex;align-items:center;justify-content:center}.notifications-dropdown{position:relative}.notifications-menu{display:none;max-width:19.6875rem;width:max-content;background-color:#fff;border-radius:0 0 .375rem .375rem;box-shadow:0 .25rem .25rem rgba(0,0,0,.25);margin-top:.375rem;z-index:21;position:absolute;text-align:left}@media only screen and (max-width: 400px){.notifications-menu{max-width:fit-content}}.notifications-menu.bs-show{display:block}.notifications-menu__text{color:#747678;font-family:interface,Helvetica,Arial,sans-serif;font-weight:400;line-height:1.5rem;padding:.6rem 1rem;margin-bottom:0}.notifications-menu__list{display:block}.notifications-menu .icon{color:#c50084;margin-right:0.25rem}.notifications-menu .dropdown-menu{padding:0;border:0.0625rem solid #eee;margin-top:revert}@media(min-width: 576px)and (max-width: 991.98px){.notifications-menu .dropdown-menu{width:min-content}}.notifications-menu .dropdown-menu a:hover{color:unset}.notifications-menu .bs-dropdown-item{border-bottom:0.0625rem solid #eee;padding:.6rem 1rem}.notifications-menu .bs-dropdown-item:last-of-type{border-bottom:none !important}.notifications-menu .bs-dropdown-item:hover{background-color:#eee}.languageSelect{border:0.0625rem solid #cccdcd;border-radius:0.1875rem;color:#333;width:13.9375rem;font-weight:700;height:fit-content;padding:0.375rem 0.6875rem 0.2625rem;padding-left:2.25rem;background-color:#fff;background-image:url("/images/globe.svg"),url("/images/chevron-down.svg");background-repeat:no-repeat;background-position:0.625rem center,calc(100% - 0.625rem) center;appearance:none}@media(min-width: 992px){.paywall-header{padding:1rem 0;margin-bottom:auto}.institution-link--text{display:none !important}.login-link{color:#2a6ebb !important;background:unset;padding:unset;width:auto}.cme-cpd{order:0}.notifications{margin-right:unset}.language-switching{top:unset;margin:0 0 0 1.1875rem}}.hide-dropdown{display:none}.institution-user .select__wrapper{top:.6875rem;margin-bottom:1.875rem}@media only screen and (max-width: 375px){.cme-cpd.pt-br{font-size:0.8125rem}.cme-cpd.pt-br .cme-cpd__credits{padding:0.375rem 0.375rem 0.4375rem}}.rf-paywall-header{padding:0;margin:0;list-style:none;display:flex;align-items:center;gap:1rem;font-weight:bold}.rf-paywall-header__link--login{color:#fff;background:#2a6ebb;border-radius:0.375rem;padding:0.5rem;margin-left:auto;width:max-content;font-weight:bold;border:none}.rf-paywall-header__mobileLoginOptions{list-style:none;padding:0.5rem 0;margin:0;text-align:right}.rf-paywall-header__mobileLoginOptions a{color:#747678;display:block;margin:0.625rem 0rem 0.5625rem;font-weight:bold}.rf-paywall-header__mobileLoginOptions li:first-child a:after{border-bottom:.0625rem solid #cccdcd;content:"";display:block;margin-left:auto;width:35%;padding-top:0.5rem}.rf-paywall--mobile{justify-content:space-between}@media(min-width: 992px){.rf-paywall--mobile{display:none}}@media(min-width: 992px){.rf-paywall-header__mobileLoginOptions{display:none !important}}.rf-paywall--desktop{margin-left:auto;width:fit-content}.rf-paywall--desktop .rf-paywall-header__item--divider{border-right:0.0625rem solid #2a6ebb;padding-right:1rem}@media(max-width: 991.98px){.rf-paywall--desktop{display:none}}.rf-paywall--loggedIn .notifications__icon{margin-left:0}@media(max-width: 991.98px){.rf-paywall--loggedIn{flex-wrap:wrap;justify-content:space-between}.rf-paywall--loggedIn>li:first-child{width:100%}}@media(min-width: 992px){.rf-paywall--loggedIn{margin-left:auto;width:fit-content}}.login-wrapper{display:flex;flex-direction:row}@media only screen and (max-width: 991.5px){.login-wrapper{flex-direction:column}}@media only screen and (min-width: 991.5px){.login-wrapper{column-gap:5.9375rem}}.bs-col{width:50%;max-width:fit-content}@media only screen and (max-width: 991.5px){.bs-col{min-width:fit-content}}.institution-title,.altLogin-grouping-nhs{margin-top:2.125rem}.institution-title.country-gb,.institution-title.country-us{margin-top:1.375rem}.bs-institution-login{background-color:#2a6ebb;border-radius:0.375rem;color:#fff;cursor:pointer;display:inline-block;margin-top:1.5rem;margin-bottom:1.875rem;padding:0.75rem 1rem;line-height:1.375rem}.bs-institution-login:hover,.bs-institution-login:focus{color:#fff}.login-form{color:#333;padding:0 0.9375rem}.login-form .x-btn:focus{color:#fff}.login-form__title{font-size:1.875rem;font-weight:400;margin-bottom:0}.login-form__intro{font-weight:400;margin-top:2.875rem;margin-bottom:60px}.login-form__input{padding-left:0.5625rem !important}.login-form__error{color:#cd202c;font-weight:700;margin-top:1.9375rem;margin-bottom:1.1875rem;padding-left:0.4375rem;display:flex}.login-form__error img{padding-right:0.4375rem;align-self:baseline}.login-form__error p{display:inline;margin-bottom:unset}.login-form label{color:#333 !important}.login-form__btn{margin-top:1.25rem;margin-bottom:3.5625rem;padding:0.75rem 1rem}.altLogin{background-color:#e5e6e6;border-radius:0.375rem;padding:1.5625rem 1.25rem;margin:2.75rem 0 2.75rem 0}.altLogin h2{color:#333;font-size:1.25rem;font-weight:700;line-height:1.4375rem;margin-bottom:1.4375rem}.altLogin ul{margin-bottom:0.75rem}.altLogin .institution-login{border-radius:0.375rem;margin-top:2.3125rem;padding:0.375rem 0.75rem;width:fit-content}.altLogin .institution-login span{text-transform:uppercase;display:block}.subscription-bp h2{color:#333;font-size:1.25rem;line-height:1.4375rem;margin-bottom:1.4375rem}.subscription-bp__image{padding-top:2.875rem;width:100%;height:auto;object-fit:cover}@media only screen and (max-width: 992px){.subscription-bp__image{width:18.75rem;margin-bottom:2rem}}@media only screen and (min-width: 992px){.subscription-bp__image{display:none}}.has-danger{border:0.125rem solid #cd202c !important}.floating-label{flex-direction:column-reverse;border:0.0625rem solid #333}#loginForm{margin-top:1.5rem}.form-group.floating-label.has-danger.last-input{margin-bottom:0 !important}.password-visible{float:right;position:relative;top:1.25rem;height:1.25rem;right:3.125rem;cursor:pointer}.open-eye-icon{background-image:url("/images/eye-open.svg");background-position:center;background-repeat:no-repeat;background-size:contain;float:right;position:relative;top:0.125rem;height:0.625rem;cursor:pointer;width:3.125rem}.closed-eye-icon{background-image:url("/images/eye-closed.svg");background-position:center;background-repeat:no-repeat;background-size:contain;float:right;position:relative;height:0.875rem;cursor:pointer;width:3.125rem}.toggle-password{margin-top:-3.125rem;border:none;padding:0;background-color:rgba(0,0,0,0);background-repeat:no-repeat}#visibility-hidden{visibility:hidden}.login-form-inputs .form-group{margin-bottom:1.25rem;margin-left:0}.login-form-inputs .form-control-feedback{font-weight:700;margin-bottom:0.8125rem}.login-form-inputs .form-group.floating-label:active{box-shadow:0 2px 2px 0 rgba(0,0,0,.14),0 1px 5px 0 rgba(0,0,0,.12),0 3px 1px -2px rgba(0,0,0,.2)}.login-form-inputs .form-control-feedback{position:relative;top:-0.5rem;display:inline}.login-form-inputs .form-control-feedback span{font-size:1rem;position:absolute;top:-0.125rem}@media all and (-ms-high-contrast: none),(-ms-high-contrast: active){.login-form-inputs input::-ms-reveal,.login-form-inputs input::-ms-clear{display:none}}.login-form-inputs .form-group{display:flex}.login-form-inputs .error-icon{background-image:url("/images/error.svg");background-position:left;background-repeat:no-repeat;background-size:contain;height:1rem;width:1rem;display:inline-block;margin-left:0.4375rem;margin-right:0.4375rem}@media(min-width: 992px){.altLogin{margin:revert;margin-bottom:auto;margin-top:3.0625rem}.altLogin__image{float:right}.login-form__title{font-size:2.5rem;margin-top:4.125rem !important}.floating-label{border:0.0625rem solid #cccdcd}.bt-black{border-top:0.0625rem solid #000}.subscription-bp{margin-top:1.25rem;margin-bottom:9.8125rem;padding-top:1.4375rem}.subscription-bp h2{margin-bottom:1.5625rem}.subscription-bp .bs-col:last-of-type{margin-left:auto}.subscription-bp__image--desktop{margin-top:2rem;margin-bottom:4rem;width:21.875rem}}@media only screen and (max-width: 992px){.bs-registration-form{padding:1rem}}.bs-registration-form .bp-form__visibility-btn{position:absolute;right:9px;z-index:1;background:no-repeat;border:none}.bs-registration-form .custom-control{margin-right:unset}@media only screen and (max-width: 991.5px){.subscription-bp__image--desktop{display:none}}.bs-registration-form__title{display:inline-block;margin-top:4.5rem !important;margin-bottom:3.125rem !important}.bs-registration-form__pw-regs{font-size:0.875rem;margin:1.75rem 0}.registration-info{background-color:#e5e6e6;border-bottom-left-radius:0.375rem;border-bottom-right-radius:0.375rem}.registration-info__img{width:100%;height:auto}.registration-info__text{padding:1.875rem 1.5625rem}.registration-info__text h2{color:#333;margin-bottom:2.375rem;font-size:1.25rem;font-weight:700}.registration-info__list{list-style-type:none;padding:0}.registration-info__list li{background-image:url("/images/check-mark.svg");background-repeat:no-repeat;background-position:left top;margin-bottom:1.5rem;padding-left:2.3125rem}.registration-wrapper{display:flex;flex-direction:row}@media only screen and (max-width: 991.5px){.registration-wrapper{flex-direction:column}}@media only screen and (min-width: 991.5px){.registration-wrapper{column-gap:3.75rem}}@media only screen and (max-width: 991.5px){.registration-wrapper .bs-col:first-of-type{order:1}}.registration-form-header{font-size:1.25rem;font-family:"interfaceregular",Arial;font-weight:700;line-height:1.75rem;padding-left:0 !important;margin-bottom:0}.bp-form__label{color:#333;display:flex;font-size:1rem;margin-left:0.625rem;padding:0.9375rem 0;position:absolute;z-index:1}.bp-form__input{border:0.0625rem solid #cccdcd;border-radius:0.1875rem;font-size:1rem;padding:1.375rem 0.3125rem 0.1875rem 0.625rem;margin-bottom:1.125rem;width:-webkit-fill-available;width:-moz-available}.bp-form__input:hover{box-shadow:0 0.125rem 0 #cccdcd}.bp-form__input::-ms-reveal{display:none}.bp-form__input-select{color:#333;background-color:#fff;font-size:1rem;padding:0.875rem 0 0.8125rem 0.6875rem;appearance:none;background-image:url("data:image/svg+xml,%3Csvg width='12' height='7' viewBox='0 0 12 7' fill='none' xmlns='http://www.w3.org/2000/svg'%3E%3Cpath d='M1 1L6.20548 6L11.411 1' stroke='%23333333'/%3E%3C/svg%3E");background-repeat:no-repeat;background-position:right 1.25rem center;height:3.125rem}.bp-form__pw-text{color:#747678;font-size:0.875rem;line-height:1.375rem;text-align:initial;margin-top:-0.1875rem;margin-bottom:1.25rem}.form-field{position:relative}.form-field .bp-form__visibility-btn{background:none;border:none;cursor:pointer;position:absolute;right:0.6875rem}.bp-form__btn{background-color:#2a6ebb;color:#fff;cursor:pointer;border:none;border-radius:0.375rem;padding:0.75rem 1rem;margin:1.5rem auto 0.625rem}.bp-form__link{background-color:#2a6ebb;display:inline-block;margin-top:1.0625rem;margin-bottom:1.8125rem;color:#fff !important;border:none;border-radius:0.375rem;padding:0.75rem 1rem}.bp-form__link:hover{color:#fff !important}.checkbox-wrapper{display:flex;column-gap:1rem;margin-bottom:0.6875rem}.checkbox-wrapper [type=checkbox]{height:1.25rem;flex:0 0 1.25rem}.checkbox-wrapper label{font-size:0.875rem;line-height:1.375rem;text-align:left}.checkbox-wrapper label a{text-decoration:underline}.registration__group .bp-form__input{margin-bottom:.625rem}.registration-return{color:#2a6ebb;cursor:pointer;display:block}.registration-return:hover{color:#c50084}.form-registration-error{display:none}.error-input{border:0.125rem solid #cd202c !important}.disabled-form{pointer-events:none;opacity:.5}.form-field small{color:#cd202c;font-weight:700;font-size:1rem;display:none;margin-bottom:0.625rem}.form-field small.error-icon{background-image:url("/images/error-icon.svg");background-repeat:no-repeat;display:inline-block;text-align:left;padding-left:1.5625rem;margin-left:0.6875rem}.form-field label.focus{font-size:0.75rem;transition:.1s ease all}.form-field label:has(+input:-webkit-autofill){font-size:0.625rem;margin-top:-0.5rem}.form-field .focus{margin-top:-0.5rem}.form-field .focus input{font-size:3rem}.registration-wrapper .bp-form__input{margin-bottom:0}.registration-wrapper .form-field{margin-top:1.25rem}.registration-wrapper .form-field .bp-form__visibility-btn{bottom:0.6875rem}.registration-wrapper .bp-form__btn--reg{background-color:#c50084;border:none;border-radius:0.375rem;color:#fff;cursor:pointer;font-size:1rem;padding:0.75rem 1rem;margin-top:1.25rem;margin-bottom:2.25rem}.registration-wrapper #alreadyRegistered{margin-top:0.9375rem}.user-login{display:block;border-top:1px solid #333}@media only screen and (max-width: 991.5px){.user-login{font-size:1rem !important;font-weight:400;margin-bottom:4.125rem}}.user-login .bp-form__link{margin-bottom:unset}.visibility-hidden{position:absolute !important;width:1px !important;height:1px !important;padding:0 !important;margin:-1px !important;overflow:hidden !important;clip:rect(0, 0, 0, 0) !important;white-space:nowrap !important;border:0 !important}.custom-reg-checkbox{display:block;position:absolute;top:0;left:0;width:1.25rem;height:1.25rem;cursor:pointer}.custom-reg-checkbox[type=checkbox]:checked+.custom-reg-checkbox__img::before{content:"";display:block;position:absolute;top:0;left:0;width:1.25rem;height:1.25rem;background-image:url("data:image/svg+xml;base64,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");background-size:cover;pointer-events:none}.label-spacing{cursor:pointer;font-size:.875rem;padding-left:2.25rem;position:relative}.inst-login{display:flex;align-items:flex-start;gap:5rem}.inst-login .form-col{flex:1}.inst-login .form-col .user-login{margin-top:2.25rem}.inst-login .img-col{flex:1;display:flex;justify-content:center;align-items:center;margin:auto}.inst-login .img-col img{width:100%;max-width:100%;height:18.75rem}.inst-login h1{margin-bottom:5.0625rem}@media only screen and (max-width: 991.5px){.inst-login{flex-direction:column;gap:initial}.form-col{flex:initial}}.inst-login-form .login-form__btn{text-transform:uppercase;margin:.5rem auto 1.875rem;border:none;border-radius:.375rem;padding:.75rem 1rem}.access-code-login{margin-bottom:3rem}#registrationRequestForm .bs-registration-form__pw-regs{margin-bottom:0;margin-top:.5rem;color:#333}#registrationRequestForm .form-field .bp-form__label{color:#757575}#registrationRequestForm .form-field .label-spacing{color:#333}.access-through-institution-page{background:#fff}.access-through-institution-page #main-content a:hover:not(.improve-bp__content-btn,.contact-us a){color:#23527c}.access-through-institution-page .breadcrumb{background:rgba(0,0,0,0);margin-bottom:0;padding-top:3.125rem;display:flex;padding-left:0;padding-bottom:0;gap:5px}.access-through-institution-page .block{display:flex;align-items:center;justify-content:space-between}.access-through-institution-page .block__content{flex:3.1}.access-through-institution-page .block__heading{color:#2a6ebb;font-style:normal;font-weight:400;font-size:2.625rem;line-height:49px;margin-bottom:.7em}.access-through-institution-page .block__aside{display:flex;align-items:center;justify-content:flex-end;flex:1;position:relative}.access-through-institution-page .block__icon--1 img:nth-child(1){position:absolute;top:4.5rem;bottom:0;margin:auto;left:2.8125rem}.access-through-institution-page .ptb-m{padding:3.125rem 0}.access-through-institution-page .info-block__content{display:flex;justify-content:center;align-items:flex-start;max-width:75%}.access-through-institution-page .info-block__content .info-block__subheading{margin-bottom:1.25rem;font-weight:400;font-size:1.125rem;color:#333;font-family:"interfaceregular",Arial,Helvetica,sans-serif;line-height:24px}.access-through-institution-page .improve-bp{display:grid;grid-template-columns:25% 75%;padding:3.125rem 0}.access-through-institution-page .improve-bp img{width:12.5rem}.access-through-institution-page .improve-bp .improve-bp__content h3{font-size:2.125rem;margin-bottom:1.25rem;color:#333}.access-through-institution-page .improve-bp .improve-bp__content p{margin-bottom:1.25rem}.access-through-institution-page .improve-bp .improve-bp__content .improve-bp__content-btn{padding:0.875rem 1.5rem 0.75rem;background:#c50084;border-radius:5px;display:inline-block;font-weight:400;font-size:1.25rem;line-height:23px;color:#fff;margin:1.875rem 0 3.75rem 0}.access-through-institution-page .bp-access .bp-access__title h3{font-weight:400;font-size:1.25rem;line-height:28px;margin-bottom:1.25rem}.access-through-institution-page .bp-access .bp-access__row{display:grid;grid-template-columns:1fr 1fr;gap:2.5rem;text-align:center;margin-top:3.75rem;padding:0 0.46875rem}.access-through-institution-page .bp-access .bp-access__row .bp-access__column-title h2{font-weight:700;font-size:1.25rem;color:#2a6ebb;margin-bottom:1.5625rem;line-height:32px}.access-through-institution-page .bp-access .bp-access__row .bp-access__column{background:#eaf1f8;border-radius:10px;padding:1.875rem 1.5625rem 5rem}.access-through-institution-page .bp-access .bp-access__row .bp-access__column p{color:#2a6ebb}.access-through-institution-page .bp-access .bp-access__row .bp-access__column .bp-access__column-icon{margin-bottom:1.5625rem}.access-through-institution-page .access-code .access-code__row{display:grid;grid-template-columns:25% 75%}.access-through-institution-page .access-code .access-code__row .access-code__column img{width:12.5rem}.access-through-institution-page .access-code .access-code__row .access-code__column h3{font-size:2.125rem;color:#333;margin-bottom:2.5rem}.access-through-institution-page .contact-us{display:flex;flex-direction:column;gap:1.875rem;padding-bottom:1.25rem}.access-through-institution-page .contact-us h3{font-size:2.125rem;line-height:40px;color:#333}.access-through-institution-page .contact-us a{padding:0.875rem 1.5rem 0.75rem;background:#c50084;border-radius:5px;color:#fff;font-weight:400;font-size:1.25rem;line-height:23px}@media only screen and (max-width: 600px){.access-through-institution-page #main-content .container{padding:0 1.875rem}.access-through-institution-page .block{flex-direction:column}.access-through-institution-page .block .block__icon--1 img:nth-child(1){left:0;right:55%}.access-through-institution-page .block .block__aside{width:100%;justify-content:center}.access-through-institution-page .info-block__content{max-width:100%}.access-through-institution-page .improve-bp{grid-template-columns:1fr}.access-through-institution-page .improve-bp .improve-bp__img{margin-bottom:1.875rem}.access-through-institution-page .improve-bp .improve-bp__content-btn{text-align:center}.access-through-institution-page .bp-access .bp-access__row{grid-template-columns:1fr;padding:0}.access-through-institution-page .access-code .access-code__row{grid-template-columns:1fr;gap:1.875rem}.access-through-institution-page .breadcrumb{padding-top:0;display:inline}.access-through-institution-page .breadcrumb span:nth-child(2){margin-left:0.3125rem;margin-right:0.3125rem}}@media only screen and (min-width: 768px)and (max-width: 1024px){.access-through-institution-page .improve-bp,.access-through-institution-page .access-code .access-code__row{grid-template-columns:35% 65%}.access-through-institution-page .block__icon--1 img:nth-child(1){left:-25%}}bp-content-filter{color:#444}bp-content-filter .bp-content-filter__input{background-color:#fff;border:.0625rem solid #cccdcd;border-radius:.1875rem 0 0 .1875rem;font-size:1rem;padding:.75rem 2rem .75rem 1rem;width:20rem;margin-bottom:1rem}bp-content-filter .bp-content-filter__label{position:relative}bp-content-filter .bp-content-filter__icon{position:absolute;top:.7rem;right:.7rem}bp-content-filter .atoz_heading{border-bottom:1px solid #e0e0e0;font-size:2.125rem;font-weight:400;letter-spacing:0;line-height:2.5rem;margin-bottom:1rem}bp-content-filter .atoz_list{list-style:none;padding:0;margin-bottom:0}bp-content-filter .atoz_list li{margin-bottom:1.5rem}bp-content-filter .atoz_list .atoz_list_text{display:block}bp-content-filter .atoz_list a .atoz_list_text{display:inline}bp-content-filter .atoz_list a{color:#2a6ebb;text-decoration:none;display:block}bp-content-filter .atoz_list li:has(.atoz_list_description) .atoz_list_text{font-weight:700}bp-content-filter .atoz_list mark{color:#c50084;background-color:rgba(0,0,0,0);font-weight:bold;padding:0}bp-local-guideline-form input,bp-local-guideline-form select{border-color:#cccdcd !important;box-shadow:none !important;border-right:1px solid 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